Bio Lecture 4,5,6 (Macro molecules)

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41 Terms

1

 What are the four classes of macromolecules?

Carbohydrates, Proteins, Nucleic Acids, Lipids.

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2

What is a polymer?

A long molecule consisting of many similar or identical building blocks (monomers) linked by covalent bonds. Ex. Carbohydrates, Proteins, Nucleic Acids

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3

What is a monomer?

Repeating units that serve as building blocks

  • Ex. Monosaccharides, Amino Acids, Nucleotides

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4

Define a dehydration reaction

  • A chemical reaction in which two monomers are covalently bonded to each other with the loss of a water molecule. Monomer → Polymer

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5

Define hydrolysis

A reaction that breaks bonds between monomers by adding water. Polymer → Monomer

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6

What are carbohydrates?

Sugars and polymers of sugars, which serve as fuel and building material

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7

What are monosaccharides?

The simplest carbohydrates, or single sugars (e.g., glucose most common monosaccharide). Monomer: monosaccharides

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8

What are disaccharides?

Two monosaccharides joined by a glycosidic linkage (e.g., sucrose). They are bonded by Covalent bond: glycosidic linkage

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9

What are polysaccharides?

Polymers of sugars that have storage and structural roles, Multiple Monosaccharides=  Polymer: polysaccharides(e.g., starch, cellulose)

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10

What are the two types of polysaccharides?

Storage polysaccharides (e.g., starch[plants], glycogen[animals]) and structural polysaccharides (e.g., cellulose(tough wall in plant cells), chitin (exoskeleton of arthropods and cell walls of many fungi)).

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11

What is a lipid?

  • A class of hydrophobic molecules that are not polymers nor monomers, including fats, phospholipids, and steroids. Bonded by Covalent Bond: Ester Linkages

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12

What is a fat (triacylglycerol)?

  • A molecule consisting of glycerol(Vertical Part) and three fatty acids(Long “tails”), used for energy storage.

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13

What is the difference between saturated and unsaturated fats?

  • Saturated fats have no double bonds between carbon atoms (solid at room temp); unsaturated fats have one or more double bonds (liquid at room temp).

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14

Trans Fats

Make “kink” Unsaturated Fat into Saturated Fat

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15
  1. What is a phospholipid?

  •  A molecule that makes up the bilayer of cell membranes, with a hydrophilic head and two hydrophobic tails(one is “kinked”).

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16

What are steroids?

Lipids characterized by a carbon skeleton consisting of four fused rings (e.g., cholesterol Component in animal cell membranes).

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17

What are proteins?

Macromolecules made of amino acids that perform a vast array of functions in living organisms. Monomer: Amino Acids . Polymer: Polypeptides . bonded by Covalent bond: Peptide Bonds’

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18

What are the 8 types of proteins

Enzymatic Proteins, Defensive Proteins, Storage Proteins, Transport Proteins, Hormonal Proteins, Receptor Proteins, Contractile and motor proteins, Structural Proteins

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19

Enzymatic Proteins

Selective acceleration of chemical reactions. Speeds up reaction by lowering activation energy, ends in “ase”. Examples: Lipase- Lipids     Lactase-Lactase 

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20

Defensive Proteins

Protection against disease. Examples: Antibodies-inactivates bacteria & viruses

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21

Storage Proteins

Storage of Amino Acids For later use, for example,Casein

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22

Transport Proteins

Transport of substances. Moves substances through the body. Example: hemoglobin carries oxygen in red blood cells.

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23

Hormonal Proteins

Coordination of an organism’s activities. Hormones are not always proteins. They are chemical messengers. Hormones don’t do things they signal other things to do things. Example: insulin secreted by pancreas signals.

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24

Receptor Proteins

Response of cell to chemical stimuli. Receivers of chemicals, allows communication between cells. examples: T cell receptors bar to antigens to trigger an immune response.

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25

Structural Proteins

Provides support, shape, and strength to cells. Example: collagen keratin.

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26

Contractile and motor proteins

Movement. responsible for undulations of Cilia and flagella. example: myosin and act and found in muscle cells.

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27

What is the structure of an amino acid?

Amino acids have a central carbon atom bonded to an amino group, a carboxyl group, a hydrogen atom, and a variable side chain (R group).

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28
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29

What are the four levels of protein structure?

  • Primary (sequence of amino acids), Secondary (Coil and folds result from hydrogen bonding

  • Alpha-helix and Beta-pleated sheets), Tertiary (3D shapeIt gives it the overall shape of the polypeptide

  • Results of from the R (side chain) group

  • Include a lot of different bonds and interactions

  • NOTE: strong covalent bonds called disulfied bridges reinforce the protein’s structure),

  • Quaternary (association of multiple polypeptidesTwo ore more polypeptide chains form one whole macromolecule

  • NOT ALL PROTIENS HAVE QUATERNARY STRUCTURE

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30

What are nucleic acids?

Polymers made of nucleotide monomers, including DNA and RNA, that store and transmit hereditary information bonded by Covalent bond: Phosphodiester Bond.

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31

What is the difference between DNA and RNA?

 DNA contains deoxyribose and the bases A, T, C, G; RNA contains ribose and the bases A, U, C, G.

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32

What are the three components of a nucleotide?

A nitrogenous base, a pentose sugar, and one or more phosphate groups

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33

What is a nucleoside

A nucleoside is a molecule consisting of a nitrogenous base attached to a sugar (ribose or deoxyribose) without a phosphate group.


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34

What are the components of a nucleoside?


A nucleoside is made up of two components:

  1. A nitrogenous base

  2. A sugar (ribose in RNA, deoxyribose in DNA)

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35

 What are pyrimidines?

Pyrimidines are nitrogenous bases that have a single six-membered ring structure. Examples of pyrimidines include cytosine, thymine (in DNA), and uracil (in RNA).


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36

Name three examples of pyrimidines.

  1. Cytosine (C) – Found in both DNA and RNA.

  2. Thymine (T) – Found only in DNA.

  3. Uracil (U) – Found only in RNA, replacing thymine.

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37

What are purines?

 Purines are nitrogenous bases that have a two-ring structure, consisting of a five-membered ring fused to a six-membered ring. Examples of purines are adenine and guanine.


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38

 Name two examples of purines.


  1. Adenine (A) – Found in both DNA and RNA.

Guanine (G) – Found in both DNA and RNA

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39

What is the difference between pyrimidines and purines?

Pyrimidines have a single six-membered ring, while purines have a two-ring structure (a five-membered ring fused to a six-membered ring). Pyrimidines include cytosine, thymine, and uracil, while purines include adenine and guanine.


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40

Which nitrogenous base is only found in RNA?


Uracil (U) is found only in RNA, where it pairs with adenine, replacing thymine, which is found in DNA

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41

 Which nitrogenous base is only found in DNA?


Thymine (T) is found only in DNA and pairs with adenine.

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