aspirin

Therapeutic Classification

Antipyretic, Non-opioid Analgesic

Mechanism of Action

•  Blocks COX enzyme and inhibits thromboxane A2 → prevents platelet aggregation
  

Therapeutic Use

Decrease risk of MI, stroke, angina, pain, fever, arthritis

Complications

GI bleed, indigestion, nausea, hypersensitivity

Contraindications

• Hypersensitivity, bleeding disorders, active GI bleed

Precautions

Liver/renal disease, alcohol use

Medication Administration:

 PO after meal or with food; chew if not extended release

Interactions

• Anticoagulants, ibuprofen (blocks platelet effect)
  
  

Nursing Interventions

• Monitor for GI bleed, I&O, hypersensitivity, toxicity signs

Client Education:

Take with full glass of water, avoid before surgery (1 week), report unusual bleeding