AMYLIN ANALOGS

1⃣ Pramlintide is classified as a(n):

✅ B) Amylin analog

2⃣ The prototype amylin analog is:

✅ C) Pramlintide

3⃣ The primary purpose of pramlintide is to:

✅ B) Slow gastric emptying

4⃣ Pramlintide is used as an adjunct to:

✅ A) Mealtime insulin

5⃣ One BLACK BOX WARNING for pramlintide is:

✅ A) Severe hypoglycemia

6⃣ The correct injection timing for pramlintide is:

✅ A) Immediately before meals

7⃣ If a meal is skipped, the patient should:

✅ A) Skip pramlintide dose

8⃣ The correct injection site for pramlintide is:

✅ A) Abdomen or thigh

9⃣ Pramlintide should be injected:

✅ A) At least 2 inches from insulin site

10⃣ A contraindication to pramlintide is:

✅ A) Gastroparesis

11⃣ The onset of pramlintide is:

✅ A) Rapid

12⃣ Which of the following is an adverse effect of pramlintide?

✅ A) Nausea

13⃣ Pramlintide is administered via:

✅ A) Subcutaneous injection

14⃣ When should oral hypoglycemics be taken with pramlintide (Type 2)?

✅ A) 1 hr before or 2 hrs after pramlintide

15⃣ Pramlintide promotes:

✅ B) Increased satiety

16⃣ Pramlintide is excreted primarily via:

✅ A) Urine

17⃣ The duration of action of pramlintide is:

✅ B) 3 hours

18⃣ A common drug interaction is with:

✅ B) Anticholinergics

19⃣ An advantage of pramlintide is:

✅ A) Can promote weight loss

20⃣ A major risk when pramlintide is used in Type 1 DM is:

✅ A) Severe hypoglycemia

21⃣ Pramlintide should NEVER be:

✅ A) Mixed in the same syringe with insulin

22⃣ Opened pramlintide vials can be stored:

✅ A) In fridge or room temp for up to 28 days

23⃣ Pramlintide works by:

✅ A) Slowing gastric emptying and suppressing glucagon

24⃣ Patients taking pramlintide should:

✅ A) Monitor blood glucose closely

25⃣ Dosing adjustments may be needed if:

✅ A) Nausea is severe

26⃣ Pramlintide crosses the placenta:

✅ A) Low potential

27⃣ The initial dose for Type 2 DM is:

✅ A) 60 mcg

28⃣ The initial dose for Type 1 DM is:

✅ B) 15 mcg

29⃣ A nurse should monitor for:

✅ A) Signs of hypoglycemia

30⃣ One of pramlintide’s benefits is:

✅ A) Helps lower postprandial blood sugar

31⃣ Which of these increases pramlintide effect:

✅ A) Anticholinergics

32⃣ Pramlintide should be used cautiously in:

✅ A) Type 1 DM patients

33⃣ An essential teaching point is:

✅ A) Do not inject if meal skipped

34⃣ One serious interaction is with:

✅ B) Alpha-glucosidase inhibitors

35⃣ An expected therapeutic effect is:

✅ A) Decreased postprandial glucose rise