Complement System & Inflammation

What is the complement system?

A group of plasma proteins that assist in killing microbes and enhancing immunity.

What is cytolysis by the complement system?

Destruction of microbes by forming membrane attack complexes (MACs).

How does complement enhance phagocytosis?

Through opsonization—coating pathogens for easier recognition by phagocytes.

How does the complement system enhance inflammation?

By promoting vasodilation and attracting immune cells.

What is the purpose of inflammation?

To dilute and remove microbes, prevent spread, and prepare tissue for repair.

What are the classic signs of inflammation?

Redness, heat, swelling, pain, and loss of function.