aerobic gram positive bacilli clibac lec - midterm

Aerobic Gram-Positive Bacilli classification

Non-spore-forming (+/-), branching actinomycetes, spore-forming Bacillus

Corynebacterium habitat

Normal skin and mucous membrane flora

Corynebacterium cell wall

m-DAP and mycolic acids

Corynebacterium catalase

Catalase positive

Corynebacterium morphology

Club-shaped gram-positive rods

Corynebacterium arrangement

Palisades, V and L forms

Corynebacterium diphtheriae disease

Diphtheria

Diphtheria toxin action

Blocks protein synthesis

Diphtheria toxin fragments

A (toxic), B (binding/entry)

Respiratory diphtheria hallmark

Gray-white pseudomembrane

Cutaneous diphtheria

Non-healing ulcers

C. diphtheriae granules

Babes-Ernst granules

C. diphtheriae culture

CTBA forms black colonies

Brown halo on CTBA

Cystinase positive

C. diphtheriae urease

Urease negative

Diphtheria toxin test

Elek test

C. jeikeium 특징

Lipophilic, urease (+), vancomycin DOC

C. urealyticum 특징

Rapid urease (+), UTI pathogen

Rothia dentocariosa 특징

Nitrate (+), esculin (+), urease (-)

Listeria monocytogenes morphology

Gram-positive coccobacillus

Listeria motility

Tumbling motility

Listeria hemolysis

Beta-hemolytic

Listeria growth

Can grow at cold temperatures

Listeria virulence factor

Listeriolysin O

Listeria high-risk groups

Pregnant, neonates, immunocompromised

Listeria neonatal disease

Early sepsis, late meningitis

Listeria adult disease

CNS infection

Listeria motility test

Umbrella pattern

Listeria biochemical tests

CAMP (+), Hippurate (+)

Listeria treatment

Ampicillin

Erysipelothrix rhusiopathiae catalase

Catalase negative

Erysipelothrix exposure

Fish/meat handlers

Erysipelothrix disease

Erysipeloid skin infection

Erysipeloid lesion

Purplish, painful, well-defined

Erysipelothrix key test

H2S positive

Erysipelothrix growth pattern

Test tube brush in gelatin

Erysipelothrix treatment

Penicillin

Arcanobacterium haemolyticum disease

Pharyngitis with rash

Arcanobacterium 특징

Catalase negative, pleomorphic

A. haemolyticum test

Reverse CAMP positive

Gardnerella vaginalis morphology

Gram-variable coccobacillus

Gardnerella disease

Bacterial vaginosis

BV 특징

Malodorous discharge, pH >4.5

Gardnerella microscopy

Clue cells

Clue cells definition

Epithelial cells coated with bacteria

Gardnerella treatment

Metronidazole

Nocardia morphology

Branching, beaded rods

Nocardia acid-fast

Weakly acid-fast

Nocardia infection

Pulmonary or cutaneous

Nocardia pulmonary disease

Bronchopneumonia

Nocardia cutaneous disease

Mycetoma

Mycetoma 특징

Draining sinuses with granules

Nocardia colony

Chalky, dry colonies

Nocardia treatment

Sulfonamides

Bacillus 특징

Spore-forming, catalase positive

Bacillus anthracis toxin

PA, EF, LF

Cutaneous anthrax lesion

Black eschar

B. anthracis colony

Medusa head

B. anthracis motility

Nonmotile

B. anthracis test

String of pearls

Bacillus cereus disease

Food poisoning

B. cereus emetic type

Fried rice vomiting

B. cereus 특징

Beta-hemolytic, motile, lecithinase (+)