stimulants intoxication & withdrawal

What is the effects of stimulants on appetite?

Low appetite

Vivid nightmares are seen in stimulant withdrawal T/F

True

MOA of amphetamine

Reverses monoamine transporters like VMAT, DAT ,NET,SERT. It increases neurotransmitters release

Intoxication of amphetamines symptoms:

1. Euphoria

2. Grandiose

3. Mydriasis

4. Hyper alert

5. Hypertension

6. Paranoia

7. Fever

Which amphetamine drug causes skin excoriations because of intoxications?

Methamphetamine

Severe intoxication of amphetamine symptoms:

1. Cardiac arrest

2. Seizures

Treatment for amphetamine intoxication

Benzodiazipines

Withdrawal of amphetamines causes what major symptom?

Meth mites

Caffeine MOA

Adenosine receptor antagonist

Intoxication of caffeine causes

Palpitation agitation insomnia tremor

Cocaine MOA

Blocks reuptake of dopamine serotonin and norepinephrine transporters.

Intoxication of cocaine causes pupils to be:

Dilated

Chronic use of cocaine can lead to

Nasal septum perforation bc of vasoconstriction leading to ischemic necrosis

Treatment of cocaine intoxication

Benzo

Cocaine intoxication leads to

Hallucination

Fornication( feeling of insects crawling )

Paranoia

Angina

Sudden cardiac death

Withdrawal from cocaine :

Restless

**hunger

**severe depression

Sleep disturbance

Nicotine MOA

Stimulates central nicotine ACH receptors

Intoxication of nicotine causes

Restlessness

Nicotine withdrawal includes:

Irritable

Low conc

Increase appetite and weight

Treatment of nicotine withdrawal

Nicotine patch or gum

Buproprion

Varenicline