Bone Tissue Chapter 6

Bone Tissue Chapter 6 -- A&P Textbook

Vitamin K

-supports bone mineralization
-may have a synergistic effect with Vitamin D
-found in Green leafy vegetables

Magnesium

-structural component of bone

Fluoride

-helps stabilize and strengthen bone mineral
-can increase density of hydroxyapatite crystals

Omega-3 Fatty Acids

-reduces inflammation that may interfere with osteoblast function
-enhance production osseous tissue since inflammation interferes with osteoblast function

Growth Hormone (GH)

-triggers chondrocyte proliferation in epiphyseal plates
-increases Ca2+ retention
-stimulates osteoblastic activity

Thyroxine

-stimulates bone growth
-promotes synthesis of bone matrix
-promotes osteoblastic activity

Sex Hormones (Testosterone & Estrogen)

-promote osteoblastic activity and production of bone matrix
-promote growth spurt
-promote conversion of epiphyseal plate to epiphyseal line

Calcitrol

-stimulates absorption of Ca2+ & PO43- from digestive tract
-active form of Vitamin D made by kidneys

Parathyroid Hormone (PTH)

-stimulates osteoclast proliferation & resorption of bone by osteoclasts
-promotes reabsorption of Ca2+ by kidney tubules

Caclitonin

-inhibits osteoclast activity & stimulates Ca2+ uptake by bones
-secreted by thyroid gland

Osteoporosis

-decrease in bone mass
-rate of bone resorption > rate of bone formation
-reduction in thickness of compact bone & number and size of trabeculae in cancellous bone