(c) the mechanism of enzyme action

How dos the enzyme substrate complex form

Surface of enzyme has an active site which attaches to the substrate molecule

Now explain in more detail how the lock and key theory happen

The tertiary structure of the active site is complementary to the substrate structure

Each enzyme is specific to the substrate it binds to

When it binds the a.a on the surface of the active site forms temporary bonds with the substrate molecule. So the r groups on the active site and substrate bond.

The reaction then catalyses where the enzyme product complex is formed it is then release from the active site once catalysed.

Explain the specificity of the enzyme

The specificity of which each enzyme is specific to the substrate it binds to

The specificity of the enzyme is where many diffferent enzymes are produced by living organisms as each enzyme catalyses one biochemical reaction at which there are thousands in a given cell

What is the activation energy

The amount of energy needed for particles to successfully colllide and react

What do enzymes do in reactions

They introduce a new reaction pathway that has a lower activation energy

What is the induced fit hypotheses

The active site changes slightly as the substrate moves in

Describe what happens in the induced fit hypotheses

The initial interaction is weak but then it rapidly induce changes in enzyme tertiary structure that strengthen the binding and puts a strain on the molecule.

This strain weakens the bonds in the substrate

This then reduces the a.e for the reaction

What happens when a substrate B enters an enzyme that is fo substrate A

Substrates which aren’t for the active site CANT format he correct bonds with the correct a.an and so the active site wont mould to fit the substrate because the tertiary structure of the enzyme wont change.