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Comprehensive flashcards covering key topics from provided lecture notes.
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Malignancies
Cells that are growing and proliferating in a disorderly fashion
Leukemia
Immature white blood cells (WBC) overgrowth
Neoplasm
Abnormal growth, either benign (growth is limited) or malignant (cancerous or with unlimited growth)
Biopsy
Surgical removal of cells for laboratory analysis
Tumor Staging
Malignant tumor's extent and progress are documented
Sarcomas
Tumors derived from connective tissue, such as bone & cartilage, muscle, blood vessels, or lymphoid tissue
TNM System
Tumor's size, any presence in the lymph nodes, cancer cells metastasized or spread to other organs
Leukemias
Distorted & uncontrolled proliferation of WBC's (leukocytes)
Acute Lymphocytic Leukemia (ALL)
Immature lymphocytes, limits production of RBC's and platelets
Acute Myeloid Leukemia (AML)
Over proliferation of granulocytes, risk for infection
Hodgkin Disease
Reed-Sternberg Cells develop (non-functioning cells)
Non-Hodgkin Disease
Malignant disorders of the lymphocytes (either B or T cells)
Osteogenic Sarcoma
Malignant tumor of long bone
Ewing Sarcoma
Bone marrow
Neuroblastoma
Tumors of the sympathetic nervous system, common in the abdomen or spinal ganglia
Rhabdomyosarcoma
Tumor of striated muscle
Nephroblastoma (Wilm's Tumor)
Malignant tumor of the kidney
Retinoblastoma
Malignant tumor of the retina of the eye
Basal Cell Carcinoma
Epithelial growth that appears as a small ulcer that does not heal
Squamous Cell Carcinoma
A tumor of the epidermis that appears as a white scaly lesion
Malignant Melanoma
A tumor originating in melanocytes or nevi that appears as a mole changing in appearance
Chief Concerns (Assessing Children with Cancer)
Weight loss, loss of appetite, easy bruising, swelling in a body part, headache, eye deviations
Physical Examination (Assessing Children with Cancer)
Swollen lymph glands, pain and swelling in a large joint, eye deviations, palpable mass in abdomen
General Signs and Symptoms of Cancer
Nausea and vomiting, weight loss, ecchymotic marks, headache, unexplained fever, bleeding/bruising, morning headaches and neurologic changes
Assessing Acute Lymphocytic Leukemia
Pallor, low-grade fever, lethargy, low thrombocyte count, petechiae, bleeding from oral mucous membranes, easy bruising on arms and legs, abdominal pain, vomiting, anorexia, bone and joint pain, headache or unsteady gait, painless, generalized swelling of lymph nodes, elevated leukocyte count, lesions on long bones, blast cells in csf
Acute Lymphocytic Leukemia Bone Marrow Aspiration
Bone marrow aspiration identifies type of wbc involved
Assessing Hodgkin Disease
One painless, enlarged, rubbery-feeling cervical lymph node followed by enlargement of other nodes and liver, spleen, bone marrow, cns, anorexia, elevated chest, sweats, sedimentation rate, anemia malaise, night
Hodgkin Disease Diagnostic Assessment
Biopsy of lymph nodes, abdominal ct, lymphangiogram
Assessing Non-Hodgkin Lymphoma
Enlarged lymph glands of neck and chest, possibly of axillary, if mediastinal lymph glands involved, cough or chest tightness, edema of face
Non-Hodgkin Lymphoma Diagnostic Assessment
Biopsy of affected lymph nodes and bone marrow
Burkitt Lymphoma
Enlarged, painless lymph node of neck or abdomen blocking a body system, growth so rapid cell mass may double in size in as few as 24 hours
Cerebellar Astrocytomas
Slow-growing, cystic tumors that arise from glial or support tissue surrounding neural cells
Medulloblastomas
Fast-growing tumors found most commonly in cerebellum
Brainstem Gliomas
Often cause paralysis of the fifth, sixth, seventh, ninth, and tenth cranial nerves
Symptoms of Increased Intracranial Pressure
Headache occurs on arising, may be intermittent throughout day, intense on straining, vomiting occurs on arising, not nauseated, will eat immediately after, diplopia, ptosis, or strabismus, papilledema
Neoplasms of the Brain Diagnostic Testing
Skull films, bone scan, ultrasound or mri, cerebral angiography, or a ct scan, possibly myelography, lumbar puncture
Assessing Osteogenic Sarcoma
Taller than average, painful, swollen site, possibly inflamed, feels warm, report of recent trauma to site
Osteogenic Sarcoma Diagnostic Testing
Elevated serum alkaline phosphatase, biopsy of site
Assessing Ewing Sarcoma
Intermittent pain at site, becomes constant and severe, onion Skin reaction on x-ray
Ewing Sarcoma Diagnostic Testing
Bone scan, bone marrow aspiration, biopsy, CT scan of lungs, and iv pyelogram or kidney MRI
Assessing Neuroblastoma
Palpable abdominal mass after possibly excessive sweating, flushed face, hypertension, possibly abdominal pain, constipation, possibly loss of motor function in lower extremities weight loss, anorexia
Neuroblastoma Diagnostic Testing
Arteriogram, ultrasound, CT, or MRI scan of chest, abdomen, pelvis, gallium bone scan, bone marrow aspiration and biopsy
Assessing Nephroblastoma (Wilms Tumor)
Palpable firm, nontender abdominal mass, possibly hematuria, Low-grade fever, anemia
Nephroblastoma (Wilms Tumor) Diagnostic Testing
CT scan or ultrasound, glomerular filtration rate or blood urea nitrogen assays
Assessing Retinoblastoma
Pupil appears white, strabismus
Retinoblastoma Diagnostic Testing
CT scan, MRI, and ultrasound
Nursing Diagnoses Regarding Cancer
Pain, imbalanced nutrition, risk for infection, disturbed body image, compromised family coping
Radiation Therapy
Changes the DNA component of a cell's nucleus and prevents replication
Chemotherapy
A chemotherapeutic agent is a drug that is capable of destroying malignant cells, ensures maximal tumor cell death with side effects like alopecia, fever, vomiting, diarrhea that can lead to dehydration
Surgery (Cancer Treatment)
An operation/procedure done for the removal of tumors
Stem Cell Transplantation
Transplantation of stem cells from the bone marrow of a well person to a child with cancer
Alopecia
Hair Loss
Cushingoid Appearance
Facial puffiness and weight gain
Gastroesophageal Reflux Assessment
Appears effortless Vomiting
Gastroesophageal Reflux Assessment
Irritable and may experience period of apnea
Gastroesophageal Reflux Assessment
Presence of gastric secretions in the esophagus
Gastroesophageal Reflux Treatment
Medication, like proton pump inhibitor omeprazole (prilosec), ranitidine (zantac)
Gastroesophageal Reflux Treatment
Laparoscopic or surgical procedure to tighten/suture esophageal sphincter
Physical Assessment of Gastrointestinal Illness in Children
Vomiting, diarrhea, poor skin turgor, dry mucous membrane, weight loss
Diagnostic Tests for Gastrointestinal Illness in Children
X-ray with contrast medium Endoscopic exam, Abdominal ultrasound MRI-magnetic resonance imaging Serum analysis Fluid concentration thru urine test
Gastroesophageal reflux (Achalasia)
Neuromuscular disturbance in which the gastroesophageal (cardiac) sphincter and the lower portion of the esophagus are lax and thus allow easy regurgitation of the gastric content into the esophagus
Pyloric stenosis
Constriction of the outlet of the stomach
Pyloric stenosis
Hypertrophy (increase in the size) or hyperplasia (overgrowth of a tissue) of the muscle surrounding the pyloric sphincter
Pyloric Stenosis Assessment
Vomiting - spitting and progress to projectile vomiting soon after the end of feeding, changes in stool, failure to gain weight, lethargy
Pyloric Stenosis Diagnostic Evaluation
Palpation of pyloric mass in conjunction with persistent, projectile vomiting is pathognomonic sign
Initial Treatment for Pyloric Stenosis
Rehydrate to correct electrolytes Correct alkalosis
Pyloric Stenosis Treatment
Surgery- Ramstedt pyloromyotomy
Hiatal Hernia
Is the intermittent protrusion of the stomach up through the esophageal opening
Hiatal Hernia Assessment
Periodic vomiting similar to esophageal reflux, pain accompanies vomiting, shortness of breath
Hiatal Hernia Diagnostic Testing
Ultrasound and Barium swallow
Hiatal Hernia Management
Baby kept in upright position to prevent condition from recurring
Hiatal Hernia Laparoscopic Surgery
Surgery - to reduce stomach ability to protrude through the diaphragm
Intussusception
Is the invagination of one portion of the intestine into another
Intussusception Assessment
Jelly like stool with blood and mucous Acute episodic abdominal pain A sausage shaped mass palpated in the right upper quadrant Vomiting up bile Lethargy
Intussusception Management
Abdominal x-ray- show obstruction and Barium or air enema (pneumatic insufflation)
Intussusception Surgical Management
Straighten the invaginated portion through surgery
Volvulus
Twisting of the intestine
Volvulus Assessment
Intense crying, pain, pulling up the legs, abdominal distention, and vomiting
Volvulus Diagnostic Testing
Abdominal x-ray and barium enema
Volvulus Medical Management
Correction of fluids and electrolytes and treatment of shock if present
Volvulus Medical Management
Rectal tube to decompress an area via intestinal intubation
Volvulus Surgical Management
Incision made in the abdominal wall via Laparotomy
Volvulus Surgical Management- Anastomosis
Joining together of two or more hollow organs
Hirschsprung's Disease
Disease of the large intestine; Absence of ganglionic innervation to the muscles of a section of the bowel
Hirschsprung's Disease Assessment
Infant do not pass meconium Development of abdominal distention
Hirschsprung's Disease Surgical Treatment
Pull through operation
Endocrine System
Ductless glands that work together with the neurologic system to regulate and coordinate a body's systems
Growth Hormones (Somatotropin)
Increases bone and cartilage growth and increase gastrointestinal absorption of calcium
Pituitary Gland
Directed by the hypothalamus, organ located in the center of the brain
Growth Hormone Deficiency
Production of the human growth hormone (somatotropin) is deficient, children cannot grow to full size
Assessment of Growth Hormone Deficiency
Normal in size and weight at birth but First few years of life, the child begins to fall below the 3rd percentile of height and weight on growth chart
Management of Growth Hormone Deficiency
To rule out kidney disease via Administration of vasopressin (pitressin); Surgery if tumor is present
Management of Growth Hormone Deficiency
IDIOPATHIC: Desmopressin an arginin vasopressin intranasally. For emergency cases it can be given IV
Diabetes Insipidus
A disease in which there is decreased release of antidiuretic hormones (ADH) by the pituitary gland
Assessment of Diabetes Insipidus
Excessive thirst (polydipsia), Polyuria, first as bedwetting in a toilet trained child
Thyroid Gland
Controlling the rate of metabolism in the body through production of thyroxine (t4) and triiodothyroxine (t3) by its follicular cells
Assessment of Thyroid Function
Radioimmunoassay of t3 and t4
Congenital hypothyroidism
Causes reduced production of t3 and t4
Congenital hypothyroidism Assessment
Child sleep excessively; the Tongue becomes enlarged; Extremities usually feels cold
Congenital hypothyroidism Management
Administration of thyroid hormones (sodium levothyroxine); Treatment may start within the 1st 1-2 weeks of life