Excretion
The process of removing metabolic wastes. Must cross a cell membrane to leave the body. Just as important as digestion in maintaining the body's internal environment.
Elimination
Removal of waste and undigested food material from the body.
Food Intake
Digestion -> Absorption -> Utilization of Nutrients by Cells -> Metabolic Wastes -> Excretion
Metabolic Wastes
Byproducts of metabolism
Metabolism
The sum total of all the chemical reactions that keep an organism alive.
3 Metabolic Wastes
Water, Carbon Dioxide, Nitrogenous Wastes
3 Nitrogenous Wastes
Urea, Ammonia, Uric Acid.
Highly toxic. During the breakdown of amino acids the nitrogen-containing amino groups are removed (deamination) and converted to…
Ammonia
Urea
Principle nitrogenous waste product in humans. Produced in the liver from ammonia. Far less toxic than ammonia and can accumulate in higher concentrations without causing tissue damage.
4 Excretory Organs
Lungs, Liver, Skin, Kidneys
Lungs
Primary site of carbon dioxide excretion. Carries out detoxification, altering harmful substances so they aren’t poisonous. Also responsible for the excretion of the volatile (turning to vapor) substances in onions, garlic, and other spices.
Liver
Largest gland in the human body. Some proteins and other nitrogenous compounds are broken down here by deamination. As a result of these reactions, urea is formed. Produces bile, helps breakdown (emulsify) lipid molecules and old red blood cells. Responsible for maintaining “normal” levels of glucose in blood. Also responsible for removing potentially hazardous chemicals from the blood. It detoxifies the blood.
Skin
Excretes water and excess minerals (calcium, potassium, sodium) through perspiration. Sweat comes out of pores in skin, mixture of 3 metabolic wastes (water, urea, salts).
Kidneys
Primary organs of the excretory system. Plays a vital role in maintaining the homeostasis of body fluids, they do this by adjusting the salt and water content of urine. Central component of urinary system. Excrete nitrogenous wastes such as urea, uric acid, and ammonium. Maintain blood volume by regulating amount of water excreted. Monitor blood composition by regulating electrolyte excretion. The kidneys monitor blood pH chiefly by regulating the excretion of certain ions, such as hydrogen (H+). NOTE: pH of blood ~ 7.4.
Renin
Kidney secretes this enzyme which helps maintain blood pressure.
Erythropoietin
Kidney secretes this growth factor which stimulates red blood cell production.
Urinary System is composed of (4 structures)
2 Kidneys, 2 Ureters, 1 Bladder, 1 Urethra
Kidneys are what type of organ
Paired
Color of Kidney and size
Each kidney is a bean-shaped, reddish-brown organs about the size of a fist.
Location of Kidney
Lie on either side of the vertebral column in a depression high on the posterior wall of the abdominal cavity
Which Kidney is higher
The left kidney is usually 1.5 – 2.0 centimeters higher than the right kidney.
Why is the left Kidney higher
The liver is on the right side so the kidney needs to be lower on the right side.
3 Main Parts of the Kidney
Renal Cortex, Renal Medulla, Renal Pelvis
Renal Cortex
Outermost region of the kidney
Renal Medulla
Inner portion of the kidney (forms striped, cone-shaped regions called renal pyramids)
Renal Pelvis
Funnel-shaped structure in center of kidney (collects urine made by kidney).
Blood enters Kidney through this
Renal Artery
Renal Artery
Responsible for transporting nutrients and wastes to the kidneys. The nutrients are used by kidneys cells to carry out their life processes.
Renal Vein
Blood leaves Kidney through this
What is removed from the kidneys by urine
Toxins, urea, water, and mineral salts
Nephron
Functional unit of the Kidney, contain more than one million each
What do Nephrons do
These tiny filtering units remove urea from the blood and produce urine, which is transported through a collecting duct to the renal pelvis.
Parts of the Nephron
Bowman’s Capsule, Glomerulus, Renal Tubule
Bowmans Capsule
Cup-shaped structure that encloses a bed of capillaries
Glomerulus
Capillary bed cluster, that receives blood from the renal artery
Renal tubule
Collecting duct, has 3 parts proximal convoluted tubule, Loop of Henle, and the distal convoluted tubule
From the Kidneys, urine travels down 2 thin tubes called
Ureters
After urine is formed, it passes through
The nephrons and down the renal tubules of the kidney.
Ureters length
8-10 inches long
Ureter function
Convery urine from the kidney to the bladder.
What causes urine to enter the bladder even if the person is laying down
Peristaltic contractions
Urinary Bladder shape
A hollow muscular organ shaped like a balloon. Is held in place by ligaments that are attached to other organs and the pelvic bones.
Function
Stores urine until it is time to be eliminated
Urinary Bladder holds
600 ml (1 pt.) of urine and becomes overdistended at 750 ml. You get the urge to void at approximately 250 ml and you become uncomfortable at approximately 500 ml.
Nerves in bladder
Alert a person when it is time to urinate, or empty the bladder.
Bladder Sphincters
Help keep urine from leaking.These muscles close tightlyaround the opening of the bladder into the urethra, the tube that allows urine to pass outside the body. When you urinate, the brain signals the bladder muscles to tighten, squeezing urine out of the bladder. At the same time, the brain signals the sphincter muscles to relax.
Urethra
A thin-walled tube that extends from the bladder to an external opening called the external urethral orifice.
Male Urethra
8 inches
Female Urethra
1.6 inches
Why are females more likely to get a UTI
The short length of the female urethra
Another name for Urination is
Micturition
Amount of urine releases per day
Eliminates from 1.5 L to 2.3 L of urine per day.
What affects amount of urine released
Depending on the amount of water taken in and the amount of water lost through respiration and perspiration.
Percentages of urine
95% water 5 % nitrogenous wastes and excess electrolytes.
pH of urine
Varies between 4.8-7.5
Urinanalysis
Diagnostic tool that involves the physical, chemical and visual examination of urine
What does Urinalysis indicate
If any abnormal substances are present in the urine and is used to diagnose illness. May provide more information about the general condition of the body than other set of tests.