Lecture 26 - Pyruvate Oxidation and the Citric Acid Cycle

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7 Terms

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Pyruvate Oxidation

  • pyruvate must be converted to acety CoA before being further oxidized in the citric acid cycle

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Final step of citric acid cycle (step 8) shows how energy is harvested

Malate is reduced via malate dehydrogenase to oxaloacetate

NAD+ is oxidized to NADH

  • 1st hydrogen of hydride ion is released

  • 2nd hydrogen is releases as a proton

<p>Malate is reduced via malate dehydrogenase to oxaloacetate</p><p>NAD<sup>+</sup> is oxidized to NADH</p><ul><li><p>1st hydrogen of hydride ion is released</p></li><li><p>2nd hydrogen is releases as a proton </p></li></ul><p></p>
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The availability of acetyl CoA determines how many intermediates are in the pathway at a given time

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Produces of 1 glucose —> glycolysis —> pyruvate oxidation —> CAC

6 CO2, 10 NADH, 2 FADH2, 4 ATP (2 ATP, 2 GTP)

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Is glucose completely oxidized at the end of the citric acid cycle?

No