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aerosol drug delivery devices
metered dose inhalers, dry powder inhalers, nebulizers
metered dose inhaler
uses propellant to deliver medication, should use spacer
MDI advantages
portable, multidose delivery capability, lower risk of contamination
MDI disadvantages
need for correct actuation and inhalation coordination, oropharyngeal drug deposition (thrush)
DPIs
breath actuated device that delivers the drug in the form of particles contained in a capsule or blister that is punctured before use
DPI advantages
breath actuated, no spacer, no holding breath, portable, no propellant
DPI disadvantages
adequate inspiratory flow required for medication delivery, may result in high pharyngeal deposition, humidity can cause powder to clump
nebulizers
transform solutions or suspensions of medications into aerosols that are optimal for deposition in lower airway
nebulizer advantages
provide therapy for pts who cannot use other methods, allow administration of large doses of medicine, no patient coordination
nebulizer disadvantages
not portable, longer setup and administration, higher cost, may need compressed air/O2
how to administer nebulized meds
put med in cup and close, attach cup to mask, activate pressure source, tell patient to breathe normally