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prokaryotic elongation factors
Ef-Tu / Ef-G
eukaryotic elongation factors
Ef1/Ef2
Ef-tu function
is a “timer” where peptide bond could only extend once the right tRNA gets added in translation
Ef-G function
uses GTP hydrolysis, acts as facilitator and ribosome has to shift forward exactly one codon to maintain proofreading of reading frame when recognized