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Anthropology
the study of man
culture
learned meanings, symbols and knowledge
Sociocultural Anthropology
studies variation in cultural behaviors among human population
Linguistic Anthropology
studies language and how it relates to culture, and the languages of non-literate people
Archaeology
focuses on cultural variations in prehistoric and historic populations by analyzing their remains
Biological Anthropology
aka physical anthropology
focuses on biological evolution of humans and human ancestors
analyzes the relationship between humans and other organisms
studies patterns of biological variation within and among human populations
Paleoanthropology
focuses of the scientific study of extinct members of homo sapien by observing fossils
primatology
focuses on the study of our primate ancestors
epistemology
a way of knowing and building knowledge
science
asks how, NOT why
the most useful scientific models make the least assumptions.
based on certain assumptions and also FAITH
oxymoron of creation science
it's an epistemology, but not a scientific one
never-ending circular argument
scientific paradigms
The practices that define a scientific discipline at a certain point in time
Discrete and culturally based
Theories
Observations that are backed up by falsifiable proof, backed up by hypotheses that haven't been rejected
Plato & the Eidos
Here, in our world, everything is a distortion of the true things (Eidos)
Eidos: the true form of something, the perfect form that exists in another world (PLATO'S CAVE)
Aristotle
Disagreed with Plato
The truth is all around us in this world, we just have to investigate it
Hypothesis
An explanation of observed facts
The Great Chain of Being
With all living things in this world, a hierarchy of perfection can be created with the most perfect at the top
Fixity of Species
Immutability of species, static view of nature
"all things created @ the beginning of creation are the same, they are all are still here and nothing has changed"
Archbishop James Usher: 4004 BC
Went through the Bible and counted the generations in it, cross referenced it with other historical events
The date that the world was created
Descartes
"I think, therefore I am"
God implanted knowledge of God into mankind, therefore we use our minds to rigorously investigate nature to "give glory to God"
Linneaus
Father of taxonomy, binomial nomenclature
- classified all things into a classification (Homo Sapien)
Didn't believe in evolution
binomial nomenclature
2-name naming system (genus + species) italicized
Homo sapiens
Species of hominid who have larger brains and to which humans belong, dependent of language and usage of tools
Lamarck
Made a model of evolution based on the Great Chain of Being; everyone progresses through the chain from the bottom up (slime mold—>worms—>grasshoppers—>etc. until humans)
Top of chain = perfection
No extinctions, just growing up and going to a different stage
Inheritance of acquired characteristics: you have to use your form/body in order to develop the characteristics, if not you are degenerating your form
Cuvier
Studied anatomy of different life forms
Catastrophism
Catastrophism
Natural disasters would wipe out all life in an area and then others would then occupy that area
Problems: why do some animals go extinct in an area but others don't? Why do some extinct forms look like living ones
Hutton
Uniformitarianism, geological processes that we can see (rain, earthquakes, etc.) occurred in he past the same way they happened today
Uniformitarianism
Assumption that geological processes that we can see (earthquakes, rain, etc.) occurred in the past the same way they happened today
Lyell and Principles of Geology
He's the father of geology, wrote "Principles of Geology"
Applies uniformitarianism to the study of geology, makes the assumption that the Earth is VERY old
Charles Darwin
Studied natural sciences, ditched minister school at Cambridge to become a Naturalist on the HMS Beagle all around the world
Wrote the "Theory of Evolution by Natural Selection" and studied finches with different beaks.
Galapagos Islands
Chain of islands near South America where Darwin developed his theory of natural selection by studying the unique life there (finches)
Thomas Malthus
"An essay on the principle of population"
Humans are stripping the world of its food supply
Because of industrial revolution, food supply was increasing arithmetically, but population was increasingly geometric
Alfred Russell Wallace
English naturalist who proposed, independently of Charles Darwin, the concept of natural selection as a mechanism for evolution and as a way to explain the great variety of living things
Evo by Natural Selection
1. Super-fecundity of species
2. Resources are limited
3. Population sizes are stable over time
4. Individuals vary
5. Variation is inherited
differential reproduction
Certain individuals with favorable trails live longer and pass it on to their kids
vestigial structures
Structure in organisms now that have no function, but their ancestors needed it
Vestigial structure that many organisms have in common suggest a common ancestor
Huntington's Chorea
Genetic disorder, inherited from parents
Late-onset neurodegenerative disease
This disease has no effect on natural selection b/c it did not affect the reproductive output
Darwin's Theoretical Problems
1. Absence of transitional forms in fossil record.
2. No answer for the source of variation.
3. How is variation inherited?
Gregor Mendel
Benedictine monk that did experiments on plants (short lifespan, large sample size, discrete traits)
Genes
DNA segments that serve as the key functional units in hereditary transmission.
Alleles
Different versions of a gene
Genotype
Any unique combination of alleles that an individual can possess that codes for a trait
Phenotype
Description of an observable trait
Homozygous (homozygote)
Any genotype where the alleles are the same. Recessive or dominant.
Heterozygous (heterozygote)
Alleles are different (Dd)
Dominant and recessive
Dominant alleles show up in phenotype when in a heterozygous genotype
Recessive alleles don't show up in heterozygous
multi-allelic
a single gene has more than 3+ alleles in a population (ABO blood type)
Codominance
A condition in which neither of two alleles of a gene is dominant or recessive.
ABO Blood groups
based on having an A, B, both or no antigens on red blood cells
The Cell
Nucleus: part of the cell containing DNA and RNA and responsible for growth and reproduction
Ribosomes: site of protein synthesis
Mitochondria: powerhouse of the cell, organelle that is the site of ATP production
Chromosomes
threadlike structures made of DNA molecules that contain the genes
Made of chromatin: very coiled up, usually before replication
Gene locus
The specific location of a gene or DNA sequence on a chromosome
homologous chromosomes
Chromosomes of the same pair at the same gene loci
Human chromosome #
46
Principle of segregation
Alleles of the same gene segregate into separate gametes
Principle of Independent Assortment
Alleles of different genes sort independently into gametes
Mitosis
Simple cell division, asexual reproduction of somatic cells
Meiosis
Sexual reproduction, done to gametes (germ cells)
Zygote
fertilized egg
cross over
Process in which homologous chromosomes exchange portions of their chromatids during meiosis.
Recombination
Segregation and independent assortment of chromosomes into gametes, which creates new combinations of DNA
Autosomes
Any chromosome that is not a sex chromosome, first 22 sets
sex chromosomes
Chromosomes that determine the sex of an individual, 23rd pair
DNA structure and functions
Double helix, double stranded, base pairing (A-T, C-G), is very stable
RNA structure and functions
Single strand, used for coding in protein synthesis
Nuclei acids
Ribose sugar, nitrogen base, and phosphate group
Polymer
DNA replacation
When DNA makes a copy of itself
Precedes mitosis + meiosis
Enzymes that help: helicase, DNA polymerase
protein synthesis
Sequence of nucleotides in DNA determines the sequence of amino acids making a polypeptide
Transcription
Making an RNA copy of DNA using messenger RNA (mRNA)
Occurs in the nucleus
DNA nucleotide "language" —> RNA nucleotide "language"
Translation
Stringing together amino acids to make polypeptide
Occurs in the cytoplasm @ ribosome
RNA nucleotide "language" —> amino acid "language"
mRNA
Transports the genetic instructions from the DNA molecule to the site of protein synthesis
tRNA
Brings amino acids to the ribosomes during protein synthesis
Ribosomes
site of protein synthesis
amino acids
The individual building blocks of proteins
20 different kinds
Codon + tRNA Anticodon
A set of 3 nucleotides that code for a specific amino acid
Mirror image of a codon
redundancy of the genetic code
More than 1 codon can code for the same amino acid
Polypeptide + Protein
Amino acids linked by peptide bonds
Gene
Sequence of nucleotides in DNA that codes for production of a unique polypeptide or RNA molecule
Coded for by more than 1 gene locus
Polygenic
describes a characteristic that is influenced by many genes and environment
Monogenic
determined by a single gene
point mutation
Affects 1 nucleotide pair in DNA
Nucleotide substitution
base-pair substitution
Exchanges one base for another, like switching an A to a G
frameshift mutation
Adding or deleting nucleotides, very big consequences since it changes reading frame
neutral mutation
a mutation that has no effect on survival or reproduction
deleterious mutation
Junk gene, a mutation has wiped out the function
Deleterious recessives: Tay Sach's disease, type O blood
Mutation in somatic cells v. Gametes
Mutation in somatic cells do not get passed onto offspring, but mutations in the gametes do
chromosomal mutation
Affects the content or the # of chromosomes
Ex: trisomy 21 - Down's syndrome
Genome
the complete instructions for making an organism, consisting of all the genetic material in that organism's chromosomes
breeding population
A group of regularly interbreeding organisms
gene pool
Aggregate representation of all the genetic material in a breeding population
gene (allele) frequency
How common a particular allele is in a population
Reported as a proportion of lol alleles @ that gene locus in population
P+Q=1
Hardy Weinberg assumptions
1. Population is very large
2. Equal # of males + females
3. All individuals mate
4. All matings are random
5. All matings produce the same # of offspring
6. All matings occur within the population
7. No forces of evolution at work
natural selection
Any factor that promotes reproductive success of an individual
Trait is good for the environment and helps the individual reproduce
sexual selection
Trait that an individual has that increases their chances of mating + passing on genes
gene drift
Random loss of alleles in a population/gene pool
Sampling error, chance event
Has the largest toll on SMALL populations
Intergenerational drift
Loss of alleles through chance events in recombination
Does not involve natural selection
Founders Effect
Loss of genetic variation that occurs as a new population is founded by a small, non-random sample of a parent population
Ex: no type B blood in Native Americans because the people that migrated to America from Asia back then were small family groups (non-random sample). By chance, none of them had the B allele
gene flow
Migration of alleles between populations
Interbreeding between populations introduces new alleles that weren't there before
Mutation
Accidents in genetic processes altering the content of genetic material, are random