The Genetic Code and Transfer RNA and Charging

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12 Terms

1
Unambigous
Each codon only specifies one amino acid
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2
Degenerate
Each amino acid can have more than one codon
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3
Comma-less/Comma-free
Adjacent codons do not overlap
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4
Redundant
Amino acids are specified by more than one mRNA codon (because of Wobble effect)
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5
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6
Transfer RNA 5’end
Phosphate group
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7
tRNA 3’ end
Hydroxyl
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8
T arm
Responsible for attaching the tRNA to your ribosome
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9
D arm
Allows amino acyl tRNA synthetase to recognize tRNA molecule (for recognition)
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10
S-Adenosyl methionine
  • Universal methyl donor w/ an essential role in yje survival of organisms

  • Important because SAM enzyme catalyzes

  • Essential in CHARGING OF tRNA

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11
Amino-acyl tRNA synthetase (ARS)
  • Primary function is to catalyze amino acetylation of tRNA

  • Essential because tRNA needs to be charged to allow tRNA to connect to anticodons to your codon sequence

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12
Charging
Amino acid and ATP bind to the active site of amino acyl AMP and other intermediates
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