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This defect encountered in pharmaceutical film coating is due to thermal expansion of tablet cores and lack of film flexibility caused by overdrying.
a.Film Cracking (Type 1)
b.Film Cracking (Type 2)
c.Logo infilling
d.Rough coating
A
This defect encountered in pharmaceutical film coating is due to core swelling caused by excessive moisture uptake into tablet cores during coating application.
a.Film Cracking (Type 2)
b.Film Cracking (Type 1)
c.Delayed dissolution for IR products
d.Rough coating.
A
This defect encountered in pharmaceutical film coating is due to accumulation of partially spray dried material within the logo, obscuring the clarity of logo design.
a.Logo infilling
b.Rough coating
c.Delayed dissolution for IR products
d.Tablet twinning
A
This defect encountered in pharmaceutical film coating is a result of partial spray drying or because of overwetting.
a.Delayed dissolution for IR products
b.Tablet twinning
c.Logo infilling
d.Rough coating
D
This defect encountered in pharmaceutical film coating is often associated with exposure of tablet cores to coating process conditions rather than a direct effect of applied coating.
a.Logo infilling
b.Rough coating
c.Delayed dissolution for IR products
d.Tablet twinning
C
The following are the steps that may be done during manufacturing in order to prevent Film Cracking (Type 1):
I. Reduce processing temperatures to minimize core thermal expansion.
II. Reduce drying conditions (or increase spray rate) so that some moisture retention in the coating occurs due to augment plasticization effects (thus increasing film flexibility)
III. Improve drying (reduce spray rate or increase temperatures) to offset overwetting.
IV. Increase pan speed to minimize dwell time in spray zone.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
C
The following are the steps that may be done during manufacturing in order to prevent Film Cracking (Type 2):
I. Improve drying (reduce spray rate or increase temperatures) to offset overwetting.
II. Increase pan speed to minimize dwell time in spray zone.
III. Use high solids coating systems to reduce moisture burden on drying process.
IV. Reduce processing temperatures to minimize core thermal expansion.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
D
The following are the steps that may be done during manufacturing in order to prevent logo infilling:
I. Minimize foam generation during preparation of coating suspension.
II. Reduce atomizing conditions and/or reduce drying conditions to minimize risk of spray drying.
III. Improve drying (reduce spray rate or increase temperatures) to offset overwetting.
IV. Increase pan speed to minimize dwell time in spray zone.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
C
The following are the steps that may be done during manufacturing in order to prevent rough coatings:
I. If roughness is caused by partial spray drying, reduce atomizing conditions and/or reduce drying conditions to minimize this effect.
II. Reduce coating solids if viscosity is too high for effective atomization.
III. If roughness is caused by overwetting, improve drying conditions in the process.
IV. Increase solids content to decrease viscosity.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
D
The following are the steps that may be done during manufacturing in order to prevent delayed dissolution for immediate release products:
I. Adjust process conditions to facilitate reduction in processing temperatures.
II. Use high solids system to enable use of low processing temperature.
III. Improve drying (reduce spray rate or increase temperatures) to offset overwetting.
IV. Increase pan speed to minimize dwell time in spray zone
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
C
The following are the steps that may be done during manufacturing in order to prevent tablet twinning
I. Avoid use of tablets with large areas of flat surfaces
II. For capsule shaped tablets, introduce a slight degree of curvature.
III. For capsule shaped tablets, create tablets with straight sides.
IV. Make the formulation tacky.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
C
The following are the steps that may be done during manufacturing in order to prevent tablet core erosion
I. Ensure tablets meet minimum friability standards.
II. Expose tablet cores to large-scale coating process conditions before core formulation is finalized.
III. Avoid use of tablets with large areas of flat surfaces.
IV. For capsule shaped tablets, create tablets with straight sides.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
C
The following are the steps that may be done during manufacturing in order to prevent tablet breakageI. Ensure tablets meet minimum breaking force standards.II. Examine pan loading and unloading procedures to minimize damage.III. Select compound radius punched to minimize sharpness of edges on tablets.IV. Include hydrophilic excipients in core formulation that can enhance adhesion of film coating
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
C
The following are the steps that may be done during manufacturing in order to prevent edge chippingI. Select compound radius punched to minimize sharpness of edges on tablets.II. Add plastically deforming excipients to minimize brittleness.III. Ensure tablet friability values are less than 0.1%.IV. For capsule shaped tablets, introduce a slight degree of curvature.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
D
The following are the steps that may be done during manufacturing in order to prevent logo bridgingI. Ensure that the core formulation is sufficiently robust to avoid the need for high compaction forces, which can negatively affect core porosity.II. Include hydrophilic excipients in core formulation that can enhance adhesion of film coatingIII. Select compound radius punched to minimize sharpness of edges on tablets.IV. Add plastically deforming excipients to minimize brittleness.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
C
The following statements regarding percutaneous absorption of drugs from transdermal patches are TRUE:
Iontophoresis enhances transport of solute molecules by creating a potential gradient through the skin tissue with an applied electrical current or voltage.
Phonophoresis enhances transport of solute molecules through the use of ultrasonic energy.
Microfabricated microneedles create conduits for transfer of drugs through the stratum corneum.
Enhancement of penetration may also be done through the use of dimethyl sulfoxide or skin ablation.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
A
The following statements regarding Transdermal delivery systems are CORRECT:
When a patient has applied a transdermal patch, it is highly recommended that they take a hot bath.
A secondary adhesive dressing may be used when applying the patch.
Transepidermal absorption involves diffusion across the skin and is limited by the stratum corneum.
Transfollicular absorption involves absorption through the use of skin appendages as a shunt.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
D
The following statements regarding reservoir-type transdermal DDS are TRUE:
Drug is contained in reservoir between backing layer and rate controlling membrane.
Release of this type of TDDS is controlled by the membrane.
This patch cannot be divided because doing so will make the dose available immediately.
An example of this patch is Duragesic®
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
A
The following statements regarding matrix-type transdermal DDS are TRUE:
The drug is evenly distributed through an adhesive matrix.
Release of this TDDS is directly proportional to the surface area.
Cutting this patch is permissible however it would decrease the efficacy of the adhesive.
An example of this patch is Catapres®.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
D
The following statements regarding adhesive-type transdermal DDS are TRUE:
Drug is homogeneously mixed with polymer based adhesive applied to impermeable backing
Release of the drug is directly proportional to the surface area and is diffusion controlled.
Cutting this patch is allowed however it would lead to decrease in the amount of drug delivered.
An example of this type is Frandol®.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
A
These are tablets compressed with the product of the partial hydrolysis of collagen. The coating facilitates swallowing, custom branding and prevent counterfeit.
a.Sugar Coated Tablets
b.Film Coated Tablets
c.Gelatin Coated Tablets
d.Enteric Coated Tablets
C
These are tablets that have delayed release properties and are coated with polymeric substances that resist solution in gastric fluid but disintegrate in the intestine.
a.Gelatin Coated Tablets
b.Sugar Coated Tablets
c.Enteric Coated Tablets
d.Compression Coated Tablets
C
These are referred to as dry coated tablets and consist of two parts, the internal core and surrounding coat.
a.Film Coated Tablets
b.Sugar Coated Tablets
c.Compression Coated Tablets
d.Enteric Coated Tablets
C
These are tablets that have been coated with concentrated sugar solution to improve compliance, aesthetic appeal, mask tastes and odors and increase stability.
a.Compression Coated Tablets
b.Gelatin Coated Tablets
c.Film Coated Tablets
d.Sugar Coated Tablets
D
These are tablets with a thin layer of polymer or mixture of polymers capable of forming a skin-like film.
a.Enteric Coated Tablets
b.Compression Coated Tablets
c.Gelatin Coated Tablets
d.Film Coated Tablets
D
This is the cheapest method of granulation and is suitable for hydro-sensitive products. This method involves two steps. One is preparing large particles called slugging. Second one is milling and screening of slugs into small granules.
a.Dry Granulation
b.Wet Granulation
c.Fluid Bed Granulation
d.NOTA
A
This method of granulation involves the addition of binding agent (hydrophilic or hydrophobic) to get wet mass. This wet mass is passed through the sieves followed by drying.
a.Dry Granulation
b.Wet Granulation
c.Fluid Bed Granulation
d.NOTA
B
It is an air suspension technique of pharmaceuticals was first reported by Wurster to coat tablets that are later used for granulating and drying of pharmaceuticals and particle/granule coating.
a.Dry Granulation
b.Wet Granulation
c.Fluid Bed Granulation
d.NOTA
C
Choose the law that is being violated/described in the following situation:
"Lucia buys her maintenance drugs from Botika Sigurado. Upon talking with the pharmacy assistant, she hands her prescription, a booklet and an ID."
a.RA 8203
b.RA 9257
c.RA 11210
d.RA 3720
B
Choose the law that is being violated/described in the following situation:
"The Food and Drug Administration was previously named the Bureau of Food and Drugs."
a.RA 8203
b.RA 3720
c.RA 9165
d.RA 10918
B
Choose the law that is being violated/described in the following situation:
"Grani went to a pharmacy to buy Valium however she forgot her prescription at home. Nevertheless, the pharmacist still dispenses her medication."
a.RA 9257
b.RA 9165
c.RA 10918
d.RA 8203
B
Choose the law that is being violated/described in the following situation:
"GRX is one of the two companies in the world manufacturing rabies vaccines. During the outbreak of rabies in the Philippines, they decided to stop selling their product without explaining to the FDA."
a.RA 7394
b.RA 11223
c.RA 11210
d.RA 9502
D
Choose the law that is being violated/described in the following situation:
"A director of a provincial hospital decides to lessen the hiring female employees this 2020."
a.RA 11210
b.RA 9502
c.RA 11223
d.RA 7394
A
Electric Double Layer Theory
Oil globules in an emulsion carry a negative charge. Water ionizes so that both hydroxyl and hydrogen ions are present.
The negative charge on the oil may come from the adsorption of hydrogen ions.
Adsorbed hydroxyl ions form a layer around the oil globule. A second layer of oppositely charged ions form a layer of liquid outside the layer of negative ions.
In this theory, electric charge is considered as a factor in emulsion stability.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
D
Oriented Wedge Theory
Monomolecular layers of emulsifying agent curved around a droplet of the internal phase of the emulsion.
In a system containing two immiscible liquids, presumably the emulsifying agent is preferentially soluble in one of the phases and is embedded more deeply and tenaciously in that phase than the other.
Certain emulsifying agents orient themselves about and within a liquid in a manner reflective of their solubility in that particular liquid.
Generally, an emulsifying agent having a greater hydrophilic than hydrophobic character will promote an o/w emulsion, and a w/o emulsion results from use of an emulsifying agent that is more hydrophobic than hydrophilic
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
A
Absorbed Film and Interfacial Tension Theory
The emulsifying agent is at the interface between the oil and water, surrounding the droplets of the internal phase as a thin layer of film adsorbed on the surface of the drops.
The film prevents contact and coalescing of the dispersed phase; the tougher and more pliable the film, the greater the stability of the emulsion.
The formation of an o/w or a w/o emulsion depends on the degree of solubility of the agent in the two phases, with water-soluble agents encouraging o/w emulsions and oil-soluble emulsifiers the reverse.
Naturally, enough of the film forming material must be available to coat the entire surface of each drop of the internal phase.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
A
Surface Tension Theory
The use of emulsifiers and stabilizers lowers the interfacial tension of the two immiscible liquid.
Lowering of interfacial tension between two liquids reduces the repellent force between the liquids and diminishing each liquids attraction for its own molecules.
Surface active agents facilitate breaking up of large globules into smaller ones.
Smaller globules have a lesser tendency to reunite or coalesce.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
A
Determining Isotonicity Value
I. In the hemolytic method, RBCs are suspended in various solutions and is observed for swelling and shrinking.
II. A RBC exposed to 0.09% NaCl solution will shrink and be crenated.
III. In the freezing point method, the constitutive property of the solution is measured.
IV. The freezing point of the blood and lacrimal fluid is -0.52F.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
C
Methods of Adjusting Isotonicity
In Class I methods, NaCl and other substances are added to the solution to lower the freezing point of the solution.
In Class II methods, water is added to the drug to make it isotonic.
An example of the Class I method is the White Vincent Method.
An example of the Class II method is the NaCl equivalent method.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
C
Class I Methods
The Liso value of uni-univalent electrolyte is 3.4
In the Liso method, the freezing point depression equation is used to calculate the amount of the isotonicity adjusting substance that must be added to hypotonic solution of drug to bring to tonicity.
Sodium chloride equivalent (E) of a drug is the amount of sodium chloride that is equivalent to 1 gram of the drug.
The E value of sodium chloride is 1.00.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
A
Class II Methods
The constant 111.11 in the equations for the second method represents the volume of solution of 0.9% NaCl that contains 1 g of NaCl
A hypertonic solution causes swelling hence Class II methods of adjusting isotonicity is used.
In Sprowl's method, the E value is fixed at 0.3.
The diluting vehicle in the White Vincent Method must absolutely be isotonic.
a.ALL statements are correct
b.Only ONE statement is correct
c.TWO statements are correct
d.THREE statements are correct
B
These systems are also known as monoliths as the drug is homogeneously dispersed in a rate controlling medium.
a.Ion exchange resin
b.OROS
c.Matrix tablet
d.Spansules
C
Capsules containing medicines (in form of granules), coated with materials having slow dissolving rates so that the medicament is delivered at different specific time.
a.Ion exchange resin
b.OROS
c.Matrix tablet
d.Spansules
D
The system consist of a drug core and an osmotically active substance (osmogen) like mannitol surrounded by a semipermeable membrane coating with an orifice of 0.4 mmmade by laser beam to facilitate drug exit.
a.Ion exchange resin
b.OROS
c.Matrix tablet
d.Spansules
B
This granulation process involves formation of spherical particles from wet granulation.
a.Spray Drying
b.Spray Congealing
c.Spray Chilling
d.Spheronization
D
This granulation process brings together highly dispersed liquids and a sufficient volume of hot air to produce evaporation and drying of liquid droplets. This can be used in encapsulation as well.
a.Spray Congealing
b.Spray Drying
c.Spray Chilling
d.Two of the Above
B
This granulation process involves melting of solids and reducing them to beads or powder by spraying the molten feed into a stream of air or other gas.
a.Spray Congealing
b.Spray Drying
c.Spray Chilling
d.Two of the Above
D
The equation for compaction is also known as:
a.Hixson Crowell
b.Henderson Hasselbalch
c.Young's
d.Heckel's
D
The following are examples of machine used in large scale mixing in Wet Granulation EXCEPT:
a.Patterson Kelley Twin-shell blender
b.Hobart Planetary Mixer
c.Glen Planetary Mixer
d.Reitz Extruder
D
Minimum effective velocity of HEPA Filter:
a.80 ± 20 ft/ min
b.90 ± 20 ft/ min
c.100 ± 10 ft/min
d.Two of the above
D
Ostwald Ripening is the destabilization of particle growth resulting from fluctuation of what parameter/s during storage?
a.Temperature
b.Pressure
c.Humidity
d.Two of the above
A
This size reduction theory states that the work required to reduce the size of a given quantity of material is constant for the same reduction ratio regardless of initial size of material.
a.Kick's Law
b.
Rittiger's Law
c.Bond's Law
d.NOTA
A
This size reduction theory states that the size reduction is directly proportional to the new surface formed.
a.Kick's Law
b.Rittiger's Law
c.Bond's Law
d.NOTA
B
This size reduction theory states that the work used to reduce the particle size is proportional to the square root of diameter of particle produced.
a.Kick's Law
b.Rittiger's Law
c.Bond's Law
d.
NOTA
C
Scopolamine (Transderm Scop®) transdermal drug delivery system can be applied to the following skin site:
Behind ear
Chest
Back
Arm
a.ALL of the choices are correct.
b.THREE of the choices are correct.
c.TWO of the choices are correct.
d.ONE of the choices is correct.
D
Clonidine (Catapres-TTS®) transdermal drug delivery system can be applied to the following skin site:
Scrotum
Arm
Chest
Thigh
a.ALL of the choices are correct.
b.THREE of the choices are correct.
c.TWO of the choices are correct.
d.ONE of the choices is correct.
D
Testosterone (Androderm®) transdermal drug delivery system can be applied to the following skin site:
Scrotum
Back
Abdomen
Thigh
a.ALL of the choices are correct.
b.THREE of the choices are correct.
c.TWO of the choices are correct.
d.ONE of the choices is correct.
B
Methylphenidate (Daytrana®) transdermal drug delivery system can be applied to the following skin site:
Hips
Arm
Chest
Back
a.ALL of the choices are correct.
b.THREE of the choices are correct.
c.TWO of the choices are correct.
d.ONE of the choices is correct.
D
Nicotine (Nicoderm®) transdermal drug delivery system can be applied to the following skin site:
Arm
Upper chest
Behind ear
Back
a.ALL of the choices are correct.
b.THREE of the choices are correct.
c.TWO of the choices are correct.
d.ONE of the choices is correct.
C
D&C Yellow 10
a.Allura Red
b.Phloxine B
c.Quinoline Yellow
d.Sunset Yellow
C
FD&C Red 40
a.Sunset Yellow
b.Erythrosine
c.Phloxine B
d.Allura Red
D
D&C Red 28
a.Allura Red
b.Erythrosine
c.Phloxine B
d.Quinoline Yellow
C
FD&C Yellow 6
a.Allura Red
b.Sunset Yellow
c.Erythrosine
d.Quinoline Yellow
B
FD&C Red 3
a.Allura Red
b.Phloxine B
c.Quinoline Yellow
d.Erythrosine
D
The term "impalpable" refer to a substance that is
a.Colorless
b.Tasteless
c.Greasy
d.Not perceptible by touch
D
Running powder consists of:
a.external disintegrant and binder
b.Internal disintegrant and colorant
c.External disintegrant and lubricant
d.Internal disintegrant and binder
C
Spans and Tweens are considered:
a.Binder
b.Surfactant
c.Lubricant
d.Colorant
B
The most commonly used diluent in powders for capsules
a.Sucrose
b.Mannitol
c.Xylitol
d.Lactose
D
The following types of lactose has the disadvantage of undergoing Maillard reaction of reaction with amine drugs and alkaline lubricants, EXCEPT:
a.Regular Lactose
b.Coarse Lactose
c.Anhydrous Lactose
d.Spray Dried Lactose
C
Percolation is a method of preparing syrups which involves passing distilled water or medicated component slowly through a bed of sucrose. Which of the following are correct?
The percolator should be cylindrical or cone shaped as it approaches the lower orifice.
Fine powdered sucrose is preferred.
Use of coarse, granular sugar will lead to coalescence forming a compact mass that is impermeable.
The percolation method is used in making syrups for compendial and confectionary use.
a.ALL statements are correct
b.ONE of the statements is correct
c.THREE of the statements are correct
d.TWO of the statements are correct
D
Liniments are alcoholic or oil-based solutions or emulsions containing therapeutic agent intended for external application. Which of the following is true regarding liniments?
Alcohol liniments are usually used for its rubefacient, counterirritant, mildly astringent effects.
Oil-based liniments are used generally for massages.
Alcohol based liniments can also serve as a protective coating on the skin.
Liniments may be liquid or semi solid in nature.
a.ALL statements are correct
b.THREE of the statements are correct
c.TWO of the statements are correct
d.ONE of the statements is correctB
B
Emulsions may be prepared with the use of one of several mixers available. Two of the most common mixers used are the impeller type and the turbine type mixer. Which of the following statements are correct regarding mechanical mixers?
Impeller type mixers are useful in high viscosity emulsions.
Turbine mixers are useful in low to medium viscosity emulsions.
Built in baffles inside mixing tanks increase the efficiency of mixing.
The degree of stirring and shear of mixers depend on speed of rotation, pattern of liquid flow, position in the container, and baffles.
a.NONE of the statements is correct
b.ONE of the statements is correct
c.TWO of the statements are correct
d.THREE of the statements are correct
D
The following statements about liposomes are true EXCEPT:
a.They are biologically inert and biodegradable.
b.Liposomes can only encapsulate water soluble drugs.
c.Liposome encapsulated drugs are less susceptible to degradation.
d.Use of liposomes can decrease a drug's toxicity.
B
Method of extraction where solid ingredients are placed in a stoppered container with the prescribed solvent and allowed to stand for a period of 3 days in warm place with frequent agitation.
a.Infusion
b.Maceration
c.Decoction
d.Digestion
B
Extraction method for water soluble and heat stable constituents of crude drugs by boiling in water for 15 minutes, cooling, straining, and passing sufficient cold water through the drug to produce desired volume.
a.Decoction
b.Digestion
c.Maceration
d.Infusion
A
Extraction by macerating crude drug in either cold or hot water for a short period of time.
a.Decoction
b.Maceration
c.Infusion
d.Digestion
C
Extraction by macerating crude drug in gentle heat.
a.Digestion
b.Infusion
c.Decoction
d.Maceration
C
Area whose air is filtered by a HEPA filter is considered to be what class of clean room?
a.Class 1
b.Class 10
c.Class 100
d.Class 1000
Feedback
C
Which of the following is/are true about the three types of glasses?
a.Type I glass has lower thermal coefficient of expansion relative to Type II and Type III glass.
b.Type II and Type III glass have lower melting point than Type I glass therefore they are easier to mold into various shapes.
c.Boric oxide is responsible to the chemical resistance, or resistance to leaching of Type II glass.
d.Two of the above
D
A suppository is a solid dosage form in which one or more API are dispersed in a suitable base and is molded or otherwise formed into a suitable shape for insertion into the rectum to provide local or systemic effect. The following are advantages of suppositories EXCEPT:
a.Partial avoidance of first pass effect which increases the blood level of drugs which are subject to first pass effect.
b.Prevent breakdown of certain drugs that are susceptible to gastric degradation.
c.Ability to administer drugs which may cause oral or gastric irritation.
d.Generally convenient to use.
D
Selection of the base to use in the formulation of an ointment depends on careful assessment of a number of factors, including the following, EXCEPT
a.Desired release rate of the substance from the ointment base.
b.Desirability of topical or percutaneous drug absorption
c.Solubility of the drug in the base
d.Characteristics of the surface to which it is applied.
C
cGMP stands for
a.Current Good Manufacturing Practice
b.Current Good Manufacturing Process
c.Current Good Manufacturing Program
d.Current Good Manufacturing Procedure
A
Sealing of ampule is done by
a.Tip Sealing
b.Softening of the neck of the ampule
c.Pull Sealing
d.A and C
D
The most common method of tableting active ingredients which are chemically incompatible.
a.Microencapsulation
b.Film coating
c.Use of stabilizers
d.Use double layer tableting
D
Coalescence of oil globules in a o/w emulsion is called:
a.Cracking
b.Inversion
c.Creaming
d.Sedimentation
A
A variation of dry gum method of preparing emulsion containing volatile oil.
a.Oil method
b.English method
c.Emulsifier in oil method
d.Forbes bottle method
D
The following excipients impart satisfactory compression characteristics to tablet formulation except:
a.Glidant
b.Disintegrants
c.Lubricant
d.Anti-adherents
B
A near saturated solution of sucrose in water.
a.Saturated Sucrose Solution, USP
b.Syrup
c.Syrup, NF
d.All of the above
C
Excessive use of binders affect:
a.Bioavailability
b.Disintegration
c.Dissolution
d.All of the above
D
HEPA filters are used for the filtration of:
a.Parenterals
b.Ophthalmics
c.Air
d.Galenicals
C
Part of tableting machine in which granules for compression is stored.
a.Hopper
b.Punch
c.Die Cavity
d.Cam tracks
A
Part of tableting machine which guides the movement of tableting punches.
a.Die Cavity
b.Punch
c.Hopper
d.Cam tracks
D
Part of tableting machine which compresses the powder/ granules for tableting into the die cavity to form the desired tablet.
a.Hopper
b.Die Cavity
c.Punch
d.Cam tracks
C
Part of tableting machine which determines the shape and size of the tablet.
a.Cam tracks
b.Die Cavity
c.Hopper
d.Punch
B
