genes to genomes
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notes for genes to genomes
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whats a gene
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whats a genome
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How do mutations arise?
1) Errors in replication of undamaged DNA, e.g. incorporation
of an incorrect nucleotide.
2) Inaccurate replication of damaged DNA.
3) Inaccurate repair of damaged DNA prior to replication.
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how can DNA damage arise?
(i)Spontaneously, due to the chemical nature of DNA and to oxidative metabolism.
(ii) As a consequence of exposure to external agents (mutagens)
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