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Cardiac output
The volume of blood ejected out of the left ventricle into the systemic vasculature per minute
Stroke volume
The volume ejected from the left ventricle per beat
Autonomic innervation and catecholamine hormones
Two main factors that influence HR
Branch from the CV control center located in the medulla to the heart
Location of autonomic neurons
End diastolic volume
Cardiac contractility
Afterload
Three main factors that regulate stroke volume
EDV
The amount of blood in the ventricle at the end of diastole (filling phase)
Cardiac contractility
The force by which the heart contracts
Afterload
The opposing pressure that the left ventricle has to overcome in order to eject blood into the aorta
Preload
Measurement of the amount of pressure/stretch placed on the walls of the ventricle
Frank-starling mechanism
If more blood fills the ventricle during diastole then there will be a greater stretch on the cardiac muscle cells
This increase in stretch causes the heart to contract with more force
The pressure in the left ventricle must be greater than the pressure in the aorta (Afterload)
In order for blood to flow out of the left ventricle into the aorta
Ejection fraction
The volume of blood ejected from the ventricles relative to the volume of blood that entered the ventricles during diastole
End systolic volume ESV
The volume of blood that remains in the ventricles after contraction
Systolic BP
The pressure that the blood exerts on the walls of the blood vessel when the heart contracts
Diastolic BP
Represents the pressure that the blood exerts on the walls of the blood vessel when the heart is relaxed
Cardiac output and total vascular resistance
Two main factors that influence BP
The diameter of the lumen of a blood vessel
Factor that influences vascular resistance
Done by the kidneys via the regulation of blood volume
The long term regulation of BP
Done by cardiac baroreceptors
Short term regulation of BP
Cardiac baroreceptors
Pressure receptors that are located in the walls of the aortic arch and the carotid sinus
Mediastinum
Central component of the thorax between the two pleural cavities
heart
Trachea
Esophagus
Great vessels
Lymph nodes
Nerves
Fat
Contents of the mediastinum
Parietal pericardium
Fibrous outer layer of the pericardium
Visceral pericardium or epicardium
Inner layer of the pericardium and forms the outer layer of the heart
Epicardium
Thin outer layer with adipose tissue and blood vessels that supply the heart and is the inner layer of the pericardium
Myocardium
Thick middle layer composed of cardiac muscle that facilitates the pumping action of the heart
Mechanical cells and conductive cells
Two categories of myocardial cells
Endocardium
Internal layer of simple squamous epithelium
Right AV valve (tricuspid)
Blood gets sent from the right atrium to the right ventricle via the
Bicuspid/mitral valve
Blood gets sent from the left atrium to the left ventricle via the
Left coronary artery
Supplies left atrium, left ventricle, and interventricular septum
Circumflex artery
Reaches posterior surface of the heart by traveling the AV groove around the L side
Left anterior descending
Supplies the left ventricle and is called the widowmaker
Right coronary artery
Supplies the right atrium, right ventricle, AV and SA nodes
Coronary sinus
Wide vein that runs transversely across the posterior surface of the heart in the coronary groove
Collects deoxygenated blood from the cardiac muscles and empties into the right atrium