Study Design & Biostats Blackboard Quiz

Barrier to evidence-based medicine where practitioners change practice because a finding is new

Press-cutting

Preliminary statistical considerations when assessing methodological quality

Power and sample size calculations; assessment of subjects lost to follow-up

Interpretation of hazard ratio 1.16 with 95% CI 0.92-1.47

Not statistically significant; increased risk of outcome in the exposed group

Factors to consider when selecting a statistical test for group differences

All of the above (independent vs dependent variable, measurement type of variables, number of groups)

When evaluating clinical literature, a deep preliminary review of the results is recommended to ensure clinical relevance

False

Gold-standard research designs for evaluating whether an environmental exposure causes disease

Case-control studies; Cohort studies

Element that is NOT part of a good clinical question

Clearly defined analysis plan

Key components to evaluate in a pharmacoepidemiology study

Research question; study design; study population; data analysis; results & interpretation