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ingestion, secretion, motility, digestion, absorption, defecation
functions of the digestive system (6)
enzymes, buffers, acids
what does the digestive system secrete?
motility
propulsion and mixing (function)
chemical and mechanical
two types of digestion
chemical
digestion that involves enzyme secretion
mechanical
digestion that involves chewing and churning
nutrients; blood and lymph
what is being absorbed and into where?
defecation
elimination of wastes (function)
mucosa, submucosa, muscularis, serosa
4 layers of the GI tract
mucosa
the innermost layer of the GI tract; has direct contact with the contents of the GI tract; subdivided into three layers
stratified squamous/simple columnar ET, lamina propria, muscularis mucosae
what are three layers of the mucosa layer?
absorption and secretion
what is the function of the stratified squamous/simple columnar ET of the mucosa layer?
5-7 days
the stratitied squamous/simple columnar layer of the mucosa is renewed every ____
areolar CT
the lamina propria is made of _______
lamina propria
has blood and lymph supply that absorbs nutrients; has MALT/lymph nodules for immunity
muscularis mucosae
thin layer of smooth muscle in the mucosa
areolar CT
the submucosa is made of ______
submucosa
layer of the GI tract that is highly vascularized
submucosal plexus
network of nerves in the submucosa that is part of the enteric NS
submucosal plexus
stimulates smooth muscle contractions and stimulates secretory cells of mucosa
muscularis
has both skeletal muscle and smooth muscle as well as the myentreric plexus
mouth, pharynx, upper esophagus, external anal sphincter
what structures are made of skeletal muscle in the muscularis?
all other locations of the GI tract (middle section)
what structures are made of smooth muscle in the muscularis?
inner circular and outer longitudinal
two layers of smooth muscle in the muscularis
myenteric plexus
stimulates the movements of GI tract (peristalsis)
parasympathetic
peristalsis is stimulated by _____ neurons
peristalsis
mixing and propulsions are referred to as ______
myenteric plexus and submucosal plexus
two parts of the enteric NS
serosa
serous membrane layer
areolar CT and simple squamous epithelium
what is the serosa made of?
visceral peritoneum
the serosa is the same as the ______
produces serous fluid, lubricates
functions of the serosa
mouth → pharynx → esophagus → stomach → small intestine → large intestine → anal canal → anus
digestive organs that form the GI tract (in order from eating to pooping)
pancreas, liver, gallbladder
accessory structures
peritoneum
serous membrane that lines the abdominopelvic cavity
peritoneal cavity; serous fluid
spaces between the parietal and visceral layer of the peritoneum (and what fills it)
greater omentum
apron extending from the transverse colon to the small intestine and stomach
lesser omentum
peritoneum folds that extends between the liver and the stomach
mesentery
fold of peritoneum that extends from post abdominal wall to surround intestines (suspends them); anchors the small intestines while still allowing for movement
mastication
chewing; mechanical breakdown of food
keep mouth moist, moistens food, lubricates (to protect esophagus)
functions of salivary glands
parotid, sublingual, submandibular
what are the three salivary glands?
H2O (99.5%)
what is saliva mostly made of?
ions, mucus (proteins, lipids, polysaccharides), immunoglobulin A
what is the other 0.5% of saliva made of?
immunoglobulin A
prevents the growth of microorganisms; found in saliva
salivary amylase
breaks down starch (carbs) into sugar (in mouth)
lingual lipase
breaks down TG (lipids); produced in the mouth but not activated until it reaches the acidic environment of the stomach
1000-1500mL/day
how much saliva is made per day?
parasympathetic NS, food, learned behavior, irritants of stomach, small intestine, nausea
what are things that stimulate saliva production?
food stimulates taste buds → salivary nucleus in brain stem → salivation
how does food promote salivation? arrows
sympathetic NS (to conserve H2O) and dehydration
what inhibits saliva production?
mumps
infection of the parotid glands; causes pain in throat, fever
inflamed testes
what can mumps cause in men?
bolus
amount of food you consume then swallow in one big bite
deglutition
swallowing
ok
read this info about deglutition:
tongue pushes bolus into oropharynx. Pons and medulla initiate a series of reflexes: breathing ceases as respiratory passage closes, uvula and soft palate move upward to close off airways, larynx moves forward and upward to cause epiglottis to fold over larynx. Once bolus passes into esophagus, all return to prior state
10” long
how long is the esophagus?
upper esophageal sphincter
as ____ relaxes, food enters the esophagus
lower esophageal sphincter
______ relaxes while swallowing to allow food into stomach
hiatal hernia
stomach protrudes upward above esophageal hiatus of diaphragm
gastroesophageal reflux disease (GERD)
lower esophageal sphincter does not close properly after bolus enters stomach; acids in stomach can creep into esophagus
avoid foods that increase acid production
neutralizers
acid reducers
3 treatments for GERD
coffee, chocolate, onions, orange juice
4 high acid foods
tums (antiacids)
example of neutralizer
H2 Blockers and Proton Pump Inhibitors
two examples of Acid Reducers
tagament, pepcid AC
examples of H2 Blockers
prilosec and protonix
two examples of proton pump inhibitors