NASAL OINTMENTS, RECTAL PREPARATIONS, VAGINAL PREPARATIONS

NASAL OINTMENTS

• Intended for local effects on the mucous membrane and underlying tissues (nasal decongestants)

• Also used for systemic absorption of drugs (nasal lining)

butorphanol tartrate

analgesic

Cyanocobalamin

• hematopoietic

• Nascobal Gel

• for intranasal administration treatment for Vit.B12 deficiency (including pernicious anemia)

Nafarelin acetate

for the treatment of endometriosis

Nicotine

adjunct in smoking cessation

RECTAL PREPARATIONS

Used in the topical treatment of anorectal conditions are Ointment, Creams, Gels, Creamlike Aerosol foam.

Ointments, Creams and Gels

• used for topical application to the perineal area and for insertion within the anal canal.

• Largely used to treat local conditions of anorectal pruritus, inflammation, and the pain and discomfort associated with hemorrhoids.

Zinc oxide

astringent

Cocoa butter and lanolin

protectant and lubricant

Pramoxine HCl

local anesthetic

Hydrocortisone

antipruritic/anti-inflammatory

Diazepam

antiepileptic

• Combination of PEG300 and 3350 

• Emulsion cream base cetyl alcohol, cetyl ester wax, white petrolatum, mineral oil

Bases for ointment and creams:

Methylparaben, propylparaben, benzyl alcohol, butyl hydroxyanisole

When antimicrobial preservatives are required:

perforated plastic tips

Rectal ointments and creams are packaged with special ____ for products to be administered into the anus, primarily in the treatment of the pain and inflammation associated with hemorrhoids.

Rectal aerosol foams

• treat minor pain, itching, swelling, and discomfort caused by hemorrhoids

• accompanied by applicators to facilitate administration.

Proctofoam-HC

Rectal aerosol foams example

VAGINAL PREPARATIONS

• Used in the topical treatment of conditions and diseases of the vulvovaginal area are Ointment, Creams, Gels, Creamlike foam. 

• Used in the topical treatment of vulvovaginal infections, vaginitis, endometrial atrophy and for contraception with spermatocidal agents.

Trichomonas vaginalis, Candida (Monilia) albicans, Haemophilus vaginalis

Usual pathogenic organisms of vulvovaginal infections and vaginitis are:

tubes

Ointment, Creams, Gels package

aerosol canisters

Vaginal foams package