Pictures - Histo (C2)

Mainly pictures for practice - credit

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Dystrophic calcification (infarctus renis anemicus)

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Hemosiderosis of spleen (Liesegang)

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Necrosis hepatis centrolobularis

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Necrosis hepatis focalis

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Infarctus renis anemicus (anaemic infarct of kidney)

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Chronic passive hyperemia of liver

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Pleuritis fibrosa (Repair by organization)

Extra note: Importance of this mechanism (repair by organization) is such that the area does not return to normal, but remains in a scarred state, so that the organ or tissue involved is permanently damaged and may be functionally impaired (defect). 

Granulation tissue grows into the fibrous exudate to liquify and engulf it (repair process). This pathological process leads to adherence of the parietal and visceral layers. From the bottom: mature fibrous CT → granulation tissue → fibrous exudate (neutrophils) in picture.

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Fibrosis myocardii

Note: myocardium of heart is locally replaced by mature fibrosis tissue with bright staining. Pink area is normal myocardial tissue while the pale is fibrous tissue. Arises secondary to cardiac stress/damage, cardiovasc. disease. The stress → substances activate fibroblasts + transdifferentiate into myofibroblasts → incr. production of proteins that are dep. in EC matrix → incr. prod. of collagenous scar tissue → myocardial fibrosis.

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Bronchopneumonia purulenta

note: from left: bruncus (round strunctures), high amount of air in the lungs are seen in middle picture, infiltrate in lumen of alveoli while normal at the top, at right: vicarious emphysema

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Pericarditis fibrinosa

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Cirrhosis hepatis (hepatitis interstitialis chronica)

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Actinomycosis (most often mandibular, less frequent maxilla) - Bildet e mest sannsynlig maxilla

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Pneumonia tuberculosa miliaris– poultry

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Pneumonia tuberculosa miliaris– hydina/poultry– ZN

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Adenoma et adenocarcinoma sebaceous gland

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squamous cell carcinoma (horse)

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Fibroma mole - tumor

• picture 1: aimlessly running of fibrous fibers, in many directions - felt structure.

• pic. 2: miscellaneous differentiation of cells - fibroblast and fibrocytes - small amount of collagen

• pic 3: cell infiltrations - heterophils, lymphocytes and macrophages and focal edema

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post traumatic focal infalmmatory reaction of myocardium

• in myocardium → round hole surrounded by expressive reaction tissue (neutrophils, macrophages + lymphocytes). Process locally → deeper areas, result of sticking the bullet in heard (foreign body). 

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Vasculitis chronica or mediocalcinosis

• tunica intigema (abnormal structure)

• t. media (smooth muscles, much bigger than normal + granulation tissue)

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Mediocalcinosis (van Kossa)

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emphysema alveolare chronic

• septa is broken and air area increased

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endobronchiolitis obliterans and peribronchitis nodosa

• bronchioles that have been infiltrated with fibroblastic granulation tissue (1)

• alveoli compressed by inflamed bronchi (2)

• outside is filled with inflammatory cells 

• the wall of bronchi is thickened (3)

• inside filled with inflammatory cells (4)

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crupous (fibrinous lobar) pneumonia and chronic interstitial pneumonia

notes:

• 1st layer: chronic intestinal pneumonia (nederst)

• 2nd layer: respond to secondary infection (exudate)

• 3rd layer: severe accumulation neutrophils

• 4th layer: fibrous (upper with all the white spaces)

Bacterial origin, or fungi chyle formation, fibrin (blood protein) escapes from bv to extravascular space - formation of mass

cant see alveoli.

Nederst på bildet: fibroblasts and fibrocytes replace lung tissue. Exudation above this tissue. Line of neutrophils above exudation. Øverst: lung tissue (alveoli) with infiltration of neutrophils and exudation.

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epulis fibromatosa

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Colitis fibrinosa (Levaditi)

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Lymphadenitis acuta simplex

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infectious bursal disease - changes in bursa (side of B-lymph production) of fabricius during infectious bursal disease (gumboro, birnavirus)

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cholangitis et pericholangitis chronica hyperplastica (coccidiosis hepatis cuniculorum)

1. bile duct wall

2. papillary folds

3. coccidia

4. epithelial cells

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Hepatitis purulenta acuta parenchymatosa (traumatic disease of forestomach)

• on the slide - cross section of cow liver with advanced traumatic reticuloperitonitis 

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Leucosis lymphadenoidea hepatis - lymphosarcoma

• one end of liver → basophilic stained tumor tissue formed by slightly differentiated lymphocytes

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Glomerulonephritis chronica

Bilde 1: hyaline in glomeruli and tubules 

bilde 2: periglomerulitis chronica, gradual fibrotization of glomeruli 

bilde 3: higher magn. of bilde 1, glomeruli with neutrophils and hyaline

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Nephrocirrhosis (nephritis interstitialis chronica)

• Ca deposition in tissue of kidney - HE staining

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Nephrocirrhosis (Van Koss)

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Meningitis spinalis purulenta 

• meninges are dilated and infiltrated by cells

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cysticercus ovis (Mozog/brain)

• at periphery of section under the meninges, there is a cysts that intrudes into the brain. 

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fibrosarcomna uteri

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hypertrophy of prostata

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Dystrophia musculorum

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trichinellosis musculorum

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Myositis sarcosporidica

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Mastitis apostematosa

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tumor mixtus mammae

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Dermatitis Eosinophilica

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Fibropapilloma mixture of fibro and papilloma