T-Cell Receptor Signaling
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4 Terms
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What are the components of the T-cell receptor complex?
T-cell receptor α and β chains (or γ and δ chains) and the CD3 complex.
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Why do T-cell receptors associate with the CD3 complex?
Because T-cell receptors have short cytoplasmic tails and require CD3 for signaling.
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What role do CD4 and CD8 play in T-cell signaling?
They act as coreceptors that enhance signaling.
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What is the outcome of T-cell receptor signaling?
Activation of T cells.
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