Magnet bio F24 Unit 4 vocab

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75 Terms

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Adenine

A nitrogenous base found in DNA and RNA that pairs with thymine (in DNA) and uracil (in RNA).

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Anticodon

A sequence of three nucleotides in tRNA that corresponds to a complementary codon in mRNA.

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Biotechnology

The use of living organisms or biological systems to develop products or technologies.

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Central dogma

The process by which genetic information flows from DNA to RNA to proteins.

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Chromosomal mutation

Any change in the structure or number of chromosomes, often resulting in genetic disorders.

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Cloning

The process of creating genetically identical copies of a biological entity.

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Codon

A sequence of three nucleotides in mRNA that specifies a particular amino acid or termination signal.

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Cytosine

A nitrogenous base found in DNA and RNA that pairs with guanine.

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Deletion (chromosomal)

A mutation where a segment of a chromosome is lost.

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Deletion (gene)

A mutation in which one or more nucleotides are removed from a gene sequence.

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Deoxyribose

The sugar molecule in the backbone of DNA that lacks one oxygen atom compared to ribose.

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DNA

Deoxyribonucleic acid, the molecule that carries the genetic instructions in all living organisms.

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DNA base pairing rules

The principle that adenine pairs with thymine and guanine pairs with cytosine in DNA.

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DNA Fingerprint

A technique used to identify individuals by analyzing variations in their DNA sequences.

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DNA ligase

An enzyme that joins two strands of DNA together by forming a phosphodiester bond.

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DNA polymerase

An enzyme responsible for forming new copies of DNA during replication.

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DNA replication

The process of making an identical copy of a DNA molecule.

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DNA Sequencing

The process of determining the precise order of nucleotides in a DNA molecule.

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Double helix

The structure of DNA, consisting of two strands twisted around each other like a spiral staircase.

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Duplication

A chromosomal mutation where a section of a chromosome is copied and inserted into the genome.

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Exon

A portion of a gene that codes for proteins and is expressed in the final mRNA transcript.

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Frameshift mutation

A genetic mutation caused by insertions or deletions that shift the reading frame of the genetic code.

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Gel Electrophoresis

A technique for separating molecules (like DNA or proteins) based on their size and charge.

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Gene mutation

A change in the sequence of nucleotides in a gene.

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Gene Therapy

A technique for correcting defective genes responsible for disease development.

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Genetic Engineering

The direct manipulation of an organism's genome using biotechnology.

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Genetic screening

Testing individuals for the presence of genetic disorders or traits.

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Genetically Modified Organism (GMO)

An organism whose genome has been altered using genetic engineering techniques.

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Genome

The complete set of genetic material in an organism.

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Guanine

A nitrogenous base found in DNA and RNA that pairs with cytosine.

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Helicase

An enzyme that unwinds the DNA double helix during replication.

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Hydrogen bonds

Weak bonds that form between the nitrogenous bases of DNA, stabilizing the double helix structure.

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Human Genome Project

A large-scale project that mapped the entire human genome.

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Insertion

A mutation where one or more nucleotides are added into the DNA sequence.

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Inversion

A chromosomal mutation where a section of a chromosome breaks off, flips, and reattaches in reverse order.

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Introns

Non-coding sections of a gene that are removed from the RNA transcript before translation.

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Lagging strand

The strand of DNA that is synthesized discontinuously during replication.

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Leading strand

The strand of DNA that is synthesized continuously during replication.

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Messenger RNA (mRNA)

The RNA molecule that carries the genetic information from DNA to the ribosome for protein synthesis.

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Mutagen

An agent, such as radiation or a chemical substance, that causes mutations.

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Mutation

A change in the DNA sequence that may lead to genetic variation or disease.

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Mutagenic factors

External agents that increase the rate of mutation, such as chemicals or radiation.

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Nitrogenous base

A molecule found in DNA and RNA that forms the rungs of the DNA ladder: adenine, thymine, cytosine, guanine, and uracil.

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Nucleotide

The basic building block of DNA and RNA, consisting of a nitrogenous base, a sugar, and a phosphate group.

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Okazaki fragments

Short sequences of DNA nucleotides synthesized on the lagging strand during DNA replication.

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Plasmid

A small, circular piece of DNA found in bacteria that can replicate independently of chromosomal DNA.

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Point mutation

A mutation affecting only one nucleotide in a gene sequence.

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Polymerase Chain Reaction (PCR)

A technique used to amplify a specific DNA segment for analysis.

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Polypeptide chain

A sequence of amino acids linked by peptide bonds that forms a protein.

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Peptide bond

The chemical bond that links amino acids together in a protein.

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Phosphodiester bond

A bond that forms the backbone of DNA and RNA by linking nucleotides together.

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Protein synthesis

The process by which cells build proteins based on genetic information in mRNA.

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Primary structure of protein

The sequence of amino acids in a protein.

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Quaternary structure of protein

The structure formed by the interaction of multiple polypeptide chains in a protein.

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Recombinant DNA

DNA that has been formed artificially by combining components from different organisms.

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Replication fork

The Y-shaped structure where DNA is split into two strands for replication.

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Restriction Enzymes

Enzymes that cut DNA at specific sequences, often used in genetic engineering.

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Ribose

The sugar component of RNA.

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Ribosomal RNA (rRNA)

A type of RNA that forms part of the ribosome and helps assemble proteins.

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Ribosome

A molecular machine in cells that translates mRNA into proteins.

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RNA

Ribonucleic acid, a molecule essential for the coding, decoding, regulation, and expression of genes.

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Secondary structure of protein

The folding of a polypeptide chain into alpha helices and beta sheets.

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Semiconservative replication

A method of DNA replication where each new DNA molecule consists of one old strand and one new strand.

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Silent mutation

A mutation that changes a nucleotide sequence but does not affect the protein produced.

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Substitution

A type of mutation where one base is replaced by another.

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Start codon

The codon (AUG) that signals the start of translation and the incorporation of methionine.

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Stop codon

A codon that signals the end of translation and release of the newly formed protein.

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Thymine

A nitrogenous base found in DNA that pairs with adenine.

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Topoisomerase

An enzyme that prevents the over-winding of DNA ahead of the replication fork.

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Transcription

The process of copying a gene's DNA sequence into mRNA.

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Transgenic organism

An organism that contains genes from another species.

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Transfer RNA (tRNA)

The RNA molecule that carries amino acids to the ribosome for protein assembly.

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Translation

The process of converting mRNA into a protein sequence.

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Translocation

A chromosomal mutation where a segment of one chromosome moves to another chromosome.

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Uracil

A nitrogenous base found in RNA that pairs with adenine instead of thymine.