Chemistry of Heterocyclic Compounds Flashcards

Flashcards on Heterocyclic Chemistry

1H-indole

A condensed 5-membered heterocycle with a nitrogen in the ring

benzo[b]furan

A condensed 5-membered heterocycle with an oxygen in the ring

benzo[b]thiophene

A condensed 5-membered heterocycle with a sulfur in the ring

Electrophilic Substitution Reactions

Reactions where an electrophile replaces a hydrogen on a molecule

N-bromosuccinimide (NBS)

A reagent used for bromination.

Nitration

A reaction involving the introduction of a nitro group (-NO2) into a molecule.

Sulfonation

A reaction involving the introduction of a sulfonic acid group (-SO3H) into a molecule.

Vilsmeier Reaction

A chemical reaction used to form carbon-carbon bonds using iminium ions and enols or enolates

Iodination

A chemical reaction used to attach an iodine atom to a molecule.

Mannich Reaction

An organic reaction used to convert a primary or secondary amine and a non-enolizable aldehyde to a β-amino-ketone

Acetylation

Introduction of an acetyl group into a molecule.

Azoles

Five-membered heterocyclic compounds containing at least one nitrogen atom and at least one other heteroatom (nitrogen, oxygen, or sulfur)

1,2-Azoles

Azoles with the heteroatoms in the 1 and 2 positions

1,3-Azoles

Azoles with the heteroatoms in the 1 and 3 positions

Triazoles

Five-membered ring with three nitrogen atoms

Tetrazole

Five-membered ring with four nitrogen atoms

Tautomerism

The existence of a molecule in two or more forms that are readily interconvertible