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Homeostasis
The ability of a body to maintain a stable internal environment
Tolerance Limits
The points just before an organism cannot survive due to environmental conditions.
Tolerance Range
The range between the minimum and maximum tolerance limits
What are some examples of tolerance limits?
Body temperature, water availability, blood glucose levels, carbon dioxide dissolved
Negative Feedback
The response reverses the stimulus
The Stimulus Response Model
Stimulus, sensory receptor, messenger, effector, response
Central Nervous System
Brain and spinal chord
Peripheral Nervous System
Peripheral nerves
Dendrites
Branchlike parts of a neuron that are specialized to receive information.
Cell Body
contains nucleus
Axon
At the opposite end of the nerve cell body. It is a long, thin fibre with branches at the end
Myelin Sheath
insulating membrane surrounding the axon in some neurons
Sensory Neuron
Long dendrite, short axon, cell body found outside the spinal cord
Interneurons
Short dendrite, short axon, entirely within CNS
Motor Neuron
Short dendrite, long axon
Synapses
The site of transmission of electric nerve impulses between two nerve cells
Neurotransmitters
chemical messengers that cross the synaptic gaps between neurons
How does the neurotransmitter leave the axon?
Exocytosis
Hormones
chemical messengers that are manufactured by the endocrine glands, travel through the bloodstream, and affect other tissues
Steroid Hormones
Lipids which are hydrophobic. Receptors inside the cell.
Peptide/Protein Hormones
Hydrophilic, in the plasma membrane
Amino Acid Derived Hormones
Hydrophilic, found on the surface
Stimulus for CO2 Regulation
Change in pH
Receptor for CO2 Regulation
Chemoreceptor cells in the medulla oblongata
Messenger for CO2 Regulation
Messages send via neurons to respiratory centre in CNS
Effector for CO2 Regulation
Diaphragm and Intercostal Muscles
Response for CO2 regulation
Breathing control
Negative effects for disruption of pH
Kidney disease, enzyme denature
Receptor for Glucoregulation (increase in glucose)
Beta cells in pancreas
Receptor for Glucoregulation (decrease in glucose)
Alpha cells in pancreas
Effectors for Glucoregulation (increase in glucose)
Beta cells produce and release insulin into blood stream
Effectors for Glucoregulation (decrease in glucose)
Alpha cells produce and release glucagon blood stream
Response for Glucoregulation (increase in blood glucose)
Insulin stimulates the uptake of glucose into liver and its storage at glycogen
Response for Glucoregulation (decrease in blood glucose)
Glucagn stimulates the conversion of glycogen in liver to glucose and its release into the blood
Effects of High Glucose &/or Low Insulin
Type 1 or Type 2 diabetes
Type 1 Diabetes
Antibodies destroy cells in the pancreas that produce insulin
Type 2 Diabetes
The body cells become resistant to the effect of insulin
Osmoregulation
Refers to the control of water levels in the blood
High Water Content
Low Osmolarity
Low Water Content
High Osmolarity
Receptor in Osmoregulation
Osmoreceptors in hypothalamus
Message in Osmoreguation (increase in water levels)
Nervous message from hypothalamus to pituitary gland to decrease ADH production which binds to kidneys
Message in Osmoregulation (decrease in water levels)
Nervous message from hypothalamus to pituitary gland to increase ADH production which binds to kidneys
Effectors in Osmoregulation (decrease in water levels)
Tubules and collecting duct found in the kidneys results in a decrease in the amount of water removed from the filtrate
Effectors in Osmoregulation (increase in water levels)
Tubules and collecting duct found in the kidney - results in an increase in the amount of water removed from the filtrate
Decrease in Osmolarity causes...
An increase in ADH causes an increase in the amount of water removed from the filtrate. This increases the amount of water taken into the blood and reduces the solute concentration of the blood.
Increase in osmolarity causes...
A decrease in ADH causes a decrease the amount of water removed from the filtrate. This decreases the amount of water taken into the blood and increases the solute concentration of the blood.
Thermoregulation effectors
Muscles, sweat glands, thyroid gland, adrenal gland
Thermoregulation Receptor
Skin and hypothalamus
Message in Thermoregulation
Nervous and hormonal: nervous to CNS, nervous to sweat glands and adrenal glands, hormonal to thyroid gland
Effector in Thermoregulation (increase in body temp)
Sweat glands begin release of sweat, adrenal glands decrease adrenalin, thyroid gland decreases thyroxin
Metabolism
Biochemical reactions occurring within cells.
Rate of metabolism controls...
Heat production and functioning of cells
Thyroxin
Controls rate of metabolism
Thyroid Stimulating Hormone
Produced by the pituitary gland, control the levels of thyroxine produced by the thyroid gland
Production of thyroxine
Monitored by both the hypothalamus and pituitary gland
Flight or Fight response
Response is a protective mechanism which enables an organism to react quickly
Effects of Adrenaline
Heart rate increases, blood pressure increases, increased metabolic rate, pupil dilation, increased blood glucose
Adrenaline
Increases oxygen exchange with the blood and increases circulation of oxygen to the cells for aerobic respiration which provides the cells with increased levels of ATP
Glucagon
Binds to liver cells and stimulates cells to convert glycogen to glucose
Insulin
Binds to liver cells and stimulates the uptake of glucose and conversion glycogen
Hypotension
Low water levels
Hypertension
High water levels
Nephrons
Which act to filter out excess water and unwanted substances. It also allows for the reabsorption of water back into the blood from the tubules
Aquaporins
Channel proteins which facilitate the rapid movement of water