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Glycolysis
cytoplasm
requires energy investment of 2 ATP to break glucose
Not much ATP is made
Phosphorylate
ADP + Phosphate group = ATP
Pyruvate Processing
mitochondria
when pyruvate is oxidized, it loses carbon and releases Co2
Insufficient ATP → acetyl-coA moves to the Kreb cycle
Sufficient ATP → acetyl-coA moves to fat synthesis for fat storage
The Krebs cycle
Mitochondria
Oxaloacetate is constantly being recycled
NADH and FADH2 are the only molecules that leave this step
ETC
electrons provide the energy needed to move protons across the membrane.
electrons get passed from protein complex to protein complex losing energy along the way
Chemiosmosis
when protons pass back across the membrane via ATP synthase pump
Oxidated Phosphorylation
potential energy is used to convert ADP and pi (inorganic phosphate into ATP)
Phosphofructokinase
a type of negative feedback enzyme that occurs in glycolysis.
uses feedback inhibition by the amount of ATP available, so the enzyme can know when to stop producing ATP
Oxidation vs reduction
Oxidation
the loss of electrons or gain of oxygen
Reduction
the gain of electrons or loss of oxygen
The process of ETC
NADH and FADH2 deliver their hydrogens to protein complexes in the inner membrane of mitochondria
The electrons get passed from protein complex to protein complex, losing energy along the way
energy is used to pump protons H+ into the intermembrane space
The final electrons acceptor is oxygen, which combines with H+ to form water
Hydrogen=
H+ (proton) + e- (electrons)
Role of oxygen in ETC
the final electron acceptor
Role of Protein complex IV
proton pump: pumps 2 protons into intramembrane space
reduction of oxygen to water
what is the ultimate goal of Cellar respiration
ATP production