Table 26.5 Distinguishing Features between Leukemoid Reaction and Chronic Myeloid Leukemia

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Last updated 5:19 AM on 2/4/26
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15 Terms

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Leukemoid reaction (Eosinophils & basophils)

Normal count morphology

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Leukemoid reaction (Neutrophil morphology)

Toxic granulation and Dohle bodies often

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Leukemoid reaction (Platelet count)

Normal

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Leukemoid reaction (Platelet morphology)

Normal

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Leukemoid reaction (Hemoglobin)

Normal

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Leukemoid reaction (LAP score)

Elevated

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Leukemoid reaction (Genetics)

Normal

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Chronic Myeloid Leukemia (Eosinophils & Basophils)

Often elevated; may show mixed granulation

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Chronic Myeloid Leukemia (Neutrophil mophology)

May see pseudo-Peger Huet forms

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Chronic Myeloid Leukemia (Platelet counts)

Elevated early; decreased late

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Chronic Myeloid Leukemia (Platelet morphology)

Possible giant, hypogranular, and/or bizarre forms

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Chronic Myeloid Leukemia (Hemoglobin)

Often anemiic

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Chronic Myeloid Leukemia (LAP score)

Decreased

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Chronic Myeloid Leukemia (Genetics)

Positive for t(9;22); BCR-ABL

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Leukemoid reaction

Refers to reactive neutrophilic leukocytosis greater than 50× 109/L with a shift to the left