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What can a deficiency of growth hormone during bone formation cause?
decreased epiphyseal plate activity
What is the first stage in the healing of a bone fracture?
formation of a hematoma
An imbalance that activates these bone cells would lead to a loss of bone density.
osteoclasts
Which hormone increases osteoclast activity to release more calcium ions into the bloodstream?
parathyroid hormone
Bones are constantly undergoing resorption (breaking bone down) for various reasons. Which of the following cells accomplishes this process?
osteoclast
Which of the following is the single most important stimulus for epiphyseal plate activity during infancy and childhood?
growth hormone
7 functions of bones
1) Support
2) Protection
3) Movement
4) Mineral and growth factor storage
5) Hematopoiesis (blood cell formation)
6) Triglyceride storage
7) Hormone production
3 types of skeletal cartilage
1. Hyaline
2. Elastic
3. Fibrocartilage
which cartilage type does the most bone develop from?
Hyaline
axial skeleton
Portion of the skeletal system that consists of the skull, rib cage, and vertebral column
appendicular skeleton
The portion of the skeleton that attaches to the axial skeleton and has the limbs attached to it
long bones
bones of the arms and legs
Flat bones
bones of the ribs, shoulder blades, pelvis, and skull
Short bones
carpals and tarsals
irregular bones
bones of the vertebrae and face
sesamoid bones
patella
spongy bone
Layer of bone tissue having many small spaces and found just inside the layer of compact bone.
compact bone
Hard, dense bone tissue that is beneath the outer membrane of a bone
structure of long bone
Epiphyses and diaphysis
Compact and spongy bone
Marrow cavity
Articular cartilage
Periosteum
osteogenic cells
stem cells that differentiate into osteoblasts
Ostebolasts
cells responsible for making bones
Osteocytes
mature bone cells
bone lining cells
flat cells found on bone surfaces where bone remodeling is not going on
Osteoclasts
cells that break down bone matrix
lamellar bone
Mature bone in sheets called lamellae. Fibers are oriented in one direction in each layer, but in different directions in different layers for strength.
endochondral ossification
Process of transforming cartilage into bone.
Intramembranes ossification
bone develops from fibrous membrane early development fetal tissue forms bones of the skull
interstitial growth
growth in length of bones
appositional growth
increase in bone thickness
growth hormone
hormone secreted by anterior pituitary gland that stimulates growth of bones
thyroid gland
produces hormones that regulate metabolism, body heat, and bone growth
how does the body control bone remodeling?
Negative feedback hormonal loop for calcium homeostasis
Responses to mechanical and gravitational forces
Role of PTH
release Calcium from bone
Wolff's Law
A bone grows or remodels in response to forces or demands placed upon it
fracture treatment
reduction and immobilization
depressed fracture
broken bone portion is pressed inward, typical of skull fracture
greenstick fracture
bending and incomplete break of a bone; most often seen in children
spiral bone fracture
ragged break when bone is excessively twisted; common sports injury
epiphyseal fracture
epiphysis separates from the diaphysis along the epiphyseal plate
comminuted fracture
fracture in which the bone is splintered or crushed
Compresion Fracture
Shattering of the bone common in the vertebrae