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H2O, ROH, RCOOH
weak nucleophile and strong base, SN1 and E1
CN-, N3-, Cl-, Br-, I-, RS-, HS-, RSH, H2S, RNH2, R3P
strong nucleophile and weak base, SN2
OH-, RO-
strong nucleophile and strong base, SN2 and E2
strong, bulky base
E2
heat
E1
strong nucleophile and strong base
SN2 and E2
weak nucleophile and strong base
SN1 and E1
strong nucleophile and weak base
SN2