Pharmacology Exam 1

A _____ is a medication used for diagnosing, curing, or treating disease

drug

From a pharmacology perspective, a drug is an endogenous or exogenous substance that has and binds a ______

receptor

True or False: Drugs are only derived from plants and animals

false

_______ is the action of drugs on living tissue

pharmacodynamics

______ is the processes of drug absorption, distribution, metabolism, and excretion

pharmacokinetics

________ is the use of drugs in treating disease

pharmacotherapeutics

_____ is the process of preparing and dispensing medicines

pharmacy

______ is the study of the amount of drug required to produce therapeutic effects (dosage)

posology

____ is the study of harmful effects of drugs on living tissue

toxicology

_____ is the influence of single genetic variations on drug effects

pharmacogenetics

_____ is the influence of the entire genome on drug effects

pharmacogenomics

_______ is the safety of drugs

pharmacovigilance

True or False: No drug has only one effect

true

True or False: Not all drugs have side effects

false

_____ is desired drugs effects or therapeutic use

drug indication

______ is undesired drug effects, including side effects, adverse effects, and toxic effects

drug contraindication

_____ effects are uncomfortable but not harmful

side

_____ effects have potential for harm

adverse

_____ effects are extremely harmful

toxic

_______ is the place where a drug exerts its effect

site of action

True or False: The site of action is not always known

true

________ is the specific site on/in/outside a cell where a drug binds and produces its effect

receptor

Receptors are most commonly ______

proteins

_______ is how a drug works at the cell and molecular levels

mechanism of action

_____ are chemical agents that selectively interact with receptors to produce specific physiologic effects

ligands

_____ is a drug that binds and produces an action

agonist

_____ binds the receptor to give the opposite pharmacologic effect

inverse agonist

______ is a drug that binds and inhibits cellular function or action

antagonist

____ blocks the binding of an agonist to its receptor without producing any receptor-mediated effect

competitive antagonist

______ binds the receptor at a different site than the agonist to limit agonist efficacy

non-competitive antagonist