Sn1, Sn2, E1, E2 bases and nucleophiles

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11 Terms

1
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at methyl halide, what is the only reaction that can occur

Sn2

2
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at a primary alkyl halide, an E2 elimination will occur if

a strong, sterically hindered base in used

3
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at a primary alkyl halide, an Sn2 substitution will occur if

a good nucleophile is used

4
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at a secondary alkyl halide, an E2 elimination will occur if

a strong base is used

5
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at a secondary alkyl halide, an Sn2 reaction will occur if

a good nucleophile that is a weak base is used in a polar aprotic solvent

6
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at a secondary alkyl halide, an Sn1 reaction and E1 reaction will occur at the same time if

a poor nucleophile that is a weak base is used in a protic solvent

7
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at a tertiary alkyl halide, an E2 elimination will occur if

a strong base is used

8
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at a tertiary alkyl halide, an Sn1 reaction along with an E1 reaction will occur if

a poor nucleophile that is a weak base is used in a protic solvent

9
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examples of good nucleophiles that are weak bases

I-, Br-, SCN-, NH3-, CH3CO2-, RS-, CN-, amines

10
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examples of good nucleophiles that are strong bases

HO-, RO-

11
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poor nucleophiles which are weak bases

H2O, ROH, RSH