antidiuretic hormone, increased levels cause the collecting duct to be more permeable to water, allowing more to be retained in case of dehydration; release by pituitary gland
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Hemodialysis
the process by which waste products are filtered directly from the patient's blood using a dialyzer when the kidneys fail
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Proximal tubule
80% water reabsorbed by osmosis as well as many other nutrients, ions, minerals; equal concentration to distal tubule
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Distial tubule
Follows the loop of Henle; equal concentration to proximal tubule although volume is much lower due to water reabsorbed in the loop of Henle.
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Loop of Henle
maintains hypertonic environment in medulla; descending limb impermeable to sodium ions and alows water to exit; ascending limb opposite
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Urinary tests
test for blood, glucose, hormones (pregnancy), drugs
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Antigen
a toxin or other foreign substance that induces an immune response in the body, especially the production of antibodies.
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MHC I
found on all body cells with a nucleus; allows immune system to distinguish "self" from "foreign"; not found on blood cells (no nucleus) so blood can be transferred between patients
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Specific immunity
specific immunity involves the production of antibodies against a specific antigens by the immune system
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Clonal selection
The process by with an specific antigen will activate a specific helper T and B cell, causing the B cell to clone itself many times to produce plasma cells that all produce one type of antibody
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Plasma cell
many rough ER and mitochondria to produce lots of antibodies (proteins); short lived cells
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Aggulination
clumping caused by antibodies binding to multiple antigens at once
injection of monoclonal antibodies like in antivenom
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Passive natural immunity
antibodies in breastmilk from mother to baby
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Active artificial immunity
vaccination and deliberate exposure to antigen
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Active natural immunity
natural exposure to antigen (infection)
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Primary immune response
first immune response, generally slow with limited antibodies produced
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Secondary immune response
usually much faster, with a large amount of antibodies produced, due to presence of memory B and helper T cells
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Exoskeletons
External skeletons that are non-living; cannot "grow" with an organism and must be shed and replaced (e.g shells)
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Endoskeletons
Internal skeletons that provide support and framework for muscles and tissue; grow with organism
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Antagonistic pairs
Pair of muscles arranged around a joint that produce opposite actions; bicep and tricep in the upper arm produce opposing effects
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Grasshopper Leg Muscles
Antagonistic pair of the flexor (pull up, tensing) and extensor (pull out, propelling out) muscle in leg
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Synovial joint
A moveable joint in the area where two bones meet; composed of the cartilage, synovial fluid and joint capsule
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Joint capsule
seals the joint space and restricts movement to avoid dislocation
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Synovial fluid
Fluid in space between bone ends that nourishes cartilage tissue and provides lubrication
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Cartilage
Hard tissue that covers the end of bones, providing shock absorption and smoother movement
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Skeletal muscle
A muscle that is attached to the bones of the skeleton and provides the force that moves the bones (NOT cardiac or smooth muscle)
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Myofibrils
Microscopic protein "myofilaments" that make up muscle fibre cells
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Myofilaments
Contractile proteins forming myofibrils; myosin and actin
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Sarcomere
Smallest contractile unit of a muscle; a section of a myofibril between two adjacent Z lines
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Sacroplasmic reticulum
Specialized endoplasmic reticulum in muscle fibre cells; stores and releases calcium ions used to trigger contraction
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Tropomyosin
Rod-like protein found on actin that covers myosin binding sites; also bound to troponin
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Troponin
A protein bound to tropomyosin with calcium ion receptors; when calcium ions bind to troponin, it causes tropomyosin to move away from myosin binding sites
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Cross bridge formation
Occurs when myosin heads bind to actin at binding sites
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Spermatogensis
The production of sperm cells in the seminiflerous tubules of the testes
A vesicle at the tip of a sperm cell that helps the sperm penetrate the egg, contains enzymes
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Acrosome reaction
First step of fertilization, in which sperm binds to zona pellucida and enzymes dissolve the zona
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Zona pellucida
A thick, transpartent coating rich in glycoproteins that surrounds an oocyte.
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Penetration
Sperm binds to docking proteins on egg; sperm DNA and centrioles enter egg cell
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Cortical reaction
cortical granules in egg fuse with plasma membrane; release of enzymes to destory sperm binding sites and prevent polyspermy
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Polyspermy
The fertilization of an oocyte by more than one sperm. Prevented in humans through the cortical reaction
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Blastocyst implantation
Blastocyst releases digestive enzymes to break down endometrium layer and implant into lining, allowing it to receive nutrients from mother
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hCG
human chorionic gonadotropin hormone, secreted by the embyro and stimulates the maintainence of the corpus luteum, which in turn secretes progesterone to maintain thick lining of uterus
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Placenta
A structure that allows an embryo to be nourished with the mother's blood supply; chorionic villi from fetus lie in the intervillus space, allowing for exchange of nutrients and waste with mother's blood
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Estrogen (Pregnancy)
Stimulate growth of uterine linging, inhibit secretion of FSH and LH
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Progesterone (Pregnancy)
Reduce uterine contractions through inhibition of oxytocin, develops breast tissue, maintain endometrium lining; secreted by corpus luteum, then placenta itself
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Oxytocin
A hormone released by the posterior pituitary that stimulates uterine contractions during childbirth in a positive feedback loop (more contractions signals release of more oxytocin)
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Prostoglandin
Hormone produced by fetus which encourage cervix to dialate and uterine contractions