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Main health risk of underweight
Increased risk of death during famine or disease due to low fat stores.
Main health risk of excessive body fat
Increased risk of chronic diseases such as diabetes, heart disease, and hypertension.
Percentage of U.S. adults overweight or obese
69%
Percentage of U.S. adults obese
42.4%
Percentage of U.S. adults severely obese (BMI ≥ 40)
9.2%
Percentage of U.S. adults underweight (BMI < 18.5)
1.5%
Percentage of U.S. children and adolescents obese
18%
Body composition
The proportion of muscle, bone, fat, and other tissues in the body.
Adipokines
Hormones produced by fat tissue that regulate inflammation and energy use.
Effect of obesity on adipokines
Increases inflammation and insulin resistance.
Central obesity
Excess fat in the abdomen and around the trunk.
Subcutaneous fat
Fat stored directly under the skin.
Visceral fat
Fat stored within the abdominal cavity around internal organs.
Metabolic syndrome
A combination of central obesity and chronic diseases.
Apple profile of fat distribution
Men and postmenopausal women.
Pear profile of fat distribution
Women in reproductive years.
BMI formula (metric)
BMI = weight (kg) / height (m)²
BMI formula (imperial)
BMI = weight (lbs) × 703 / height (in)²
BMI range for underweight
< 18.5
BMI range for normal weight
18.5 - 24.9
BMI range for overweight
25 - 29.9
BMI range for obesity
≥ 30
Waist circumference risk for men
≥ 40 inches (102 cm)
Waist circumference risk for women
≥ 35 inches (88 cm)
Waist circumference indication
Degree of central obesity and related disease risk.
Indicators for obesity risk
BMI, waist circumference, and disease risk profile.
Main methods to assess body fat
Waist circumference, skinfold test, and DEXA scan.
Skinfold test
Measures thickness of skin and subcutaneous fat.
DEXA
Used for measuring body fat distribution and bone density.
Ideal body fat level
Enough to support health, not for appearance.
Body fat loss improving health risks
5-10% of body weight.
BMI indicating urgent need for weight loss
≥ 30 or 25-29.9 with risk factors.
Common diseases associated with obesity
Type 2 diabetes, heart disease, hypertension, gallstones, stroke.
Relationship between obesity and inflammation
Obesity causes inflammatory adipokines and insulin resistance.
Can a person with obesity be healthy?
Possibly, if metabolic indicators are normal.
Can a person with normal weight be unhealthy?
Yes, if they have metabolic diseases or central fat.
Energy balance
Energy in = Energy out.
When energy in > energy out
Fat storage increases.
When energy in < energy out
Fat stores are used for energy.
Three components of energy out
Basal metabolism, voluntary activity, thermic effect of food.
Basal metabolic rate (BMR)
BMR percentage of total energy
60-70%
Factors affecting BMR
Age, gender, body size, genetics, temperature, hormones, activity level.
Thermic Effect of Food (TEF)
Energy required to digest, absorb, and process food (~10% of meal energy).
Age effect on energy need
BMR decreases about 5% per decade after age 30.
Factors used in estimating energy requirements (EER)
Age, gender, weight, height, and physical activity.
Physical activity levels for EER
Sedentary, moderately active, and active.
Estimating daily calories for men
EER ± 200 calories.
Estimating daily calories for women
EER ± 160 calories.
Hunger hormone
Ghrelin.
Production site of ghrelin
The stomach.
Appetite
The psychological desire for food.
Hunger
The physiological need for food.
Satiation
The feeling of fullness during a meal that leads to stopping eating.
Satiety
The lasting feeling of fullness between meals.
Appetite suppressing hormone
Leptin.
Macronutrient with greatest satiating effect
Protein.
Nutrients promoting longer satiety
Protein, complex carbs, and soluble fiber.
Set-Point Theory
The body resists weight change by adjusting metabolism to maintain a set weight.
Thermogenesis
Generation of heat during metabolism.
Brown Adipose Tissue (BAT)
Fat that burns calories to produce heat.
Intestinal microbiota theory of obesity
Certain gut bacteria affect body weight and fat storage.
Role of gut bacteria in weight
Affect energy extraction, storage, and inflammation.
Genetics contribution to obesity risk
30-70% chance if one parent is obese.
Environmental cues to overeating
Large portions, stress, food availability, and variety.
Neurotransmitter linked to food pleasure
Dopamine.
Physical inactivity contribution
Lower energy expenditure and weight gain.
Food deserts
Areas lacking access to affordable, healthy foods.
National goals to reduce obesity
Promote activity, improve food access, and create healthy environments.
Calculating calorie cost of an activity
Activity factor × weight (lbs) × minutes.
Minutes of moderate activity to prevent weight gain
150-250 minutes.
Minutes per week to maintain weight loss
>250 minutes.
Calories equal to one pound of body fat
3,500 calories.
Recommended rate of weight loss
1-2 pounds per week.
Weight loss improving health outcomes
3-5% of body weight.
Key strategies for healthy weight loss
Balanced diet, physical activity, and behavior modification.
Calorie reduction recommended for BMI ≥ 35
Reduce up to 1000 kcal/day.
Calorie reduction recommended for BMI 25-35
Reduce 500-750 kcal/day.
Safe calorie range for men during weight loss
1500-1800 kcal/day.
Safe calorie range for women during weight loss
1200-1500 kcal/day.
Healthy eating habits for weight loss
Eat more fruits, vegetables, legumes, whole grains, and lean proteins.
Foods to be reduced for weight loss
Saturated fat, sodium, refined grains, and sugary foods.
Why should portion size be controlled?
To prevent excess calorie intake.
Low energy density foods
Foods high in water and fiber, low in fat.
High energy density foods
Foods high in fat and low in water (e.g., fried foods).
Difference between energy density and nutrient density
Energy density = calories per gram; nutrient density = nutrients per calorie.
Snacks for weight control should include
Low solid fats and low added sugars.
Best beverages for weight loss
Water, low-fat milk, unsweetened tea.
How does alcohol affect weight?
Adds empty calories and promotes fat storage.
Calories provided by alcohol per gram
7 kcal/gram.
Nonnutritive sweeteners
Artificial sweeteners that provide few or no calories.
Are nonnutritive sweeteners risk-free?
Effects on gut microbiota and appetite are under study.
Advantages of prepared meal plans
Convenient and support calorie control.
Disadvantage of prepared meal plans
Expensive and may not teach long-term eating habits.
What happens to the body during fasting?
Liver glycogen is used up; body uses protein for glucose.
Why can't fat directly provide glucose?
Fatty acids cannot be converted to glucose.
Ketone bodies
Compounds made from fat during low carb intake or fasting.
How long can an average person survive without food using fat stores?
6-8 weeks.
Side effects of prolonged fasting
Nutrient loss, slowed metabolism, acid-base imbalance, and overeating rebound.
What happens to excess dietary protein?
Converted to fat after removing nitrogen.