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know name, functions, and conditions associated with underconsumption and overconsumption
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how many calories do vitamins yield
none
why are vitamins organic
they contain carbon
what are the fat soluble vitamins
K, A, D, E
why does vitamin b4 not exist anymore
because it is now classified as a nucleotide (adenine)
where are fat soluble vitamins stored
in liver and fat cells
what is hypervitaminosis
vitamin toxicity
water soluble vitamins stay in the body for ___ time, so they are ___ likely to cause toxicity
less, less
because water soluble vitamins don’t stay in the body for very long, you are at an increased risk for ___
deficiency
how many chemical forms does vitamin A have
3
what is the most active form of vitamin A
retinol
integrity of epithelial cells
bone growth
cell membrane stability
acne medication
vision
immune function
functions of vitamin a
excess scar tissue in liver
cirrhosis
in early stages of deficiency, you could get night blindness
vitamin A (retinol)
what is the structure that uses vitamin a the most
the eye
xerophthalmia
dry eye condition
what happens in long term vitamin a deficiency
permanent loss of vision and dry eyes
liver damage (scarring)
birth defects
symptoms of vitamin a toxicity
is beta carotene supplements recommended to the general public
no
what happens if a smoker takes beta carotene
they could increase risk of lung cancer
cholecalciferol
other name for vitamin d
regulation of calcium metabolism
stimulates kidneys to conserve calcium
stimulates calcium release from bone to blood levels
functions of vitamin d
what happens to the requirement of intake for vitamin d while you age
it increases
where do we get most of our vitamin d from in food
from fortified foods
cholesterol in skin combines with ultraviolet rays
converted into precursor of vitamin d
eventually makes its way into kidneys
converted into active form
how we make vitamin d
what is the active form of vitamin d
d3
a disease characterized by softening and deformity of long bone
inability to deposit calcium unto newly formed bone
called bow legs
rickets
softening of bone caused by decalcification
osteomalacia
calcification
soft tissue turns hard
which vitamin is considered the number one antioxidant in the body
vitamin e
what is the name of the group of compounds that make up vitamin e
tocopherols
what are the four types of tocopherols
alpha beta gamma and delta
when free radicals cause oxidative stress, what stops the free radicals
anti oxidants
antioxidant
enhances immune function
required for nerve cell development (fetal progamming)
functions of vitamin e
anemia
ataxia
reproductive failure
impaired vision
symptoms of vitamin e
what is ataxia
loss of muscle coordination and reflexes
blod clotting
activates proteins to make fibrin and forms blood clots
functions of vitamin k
what is the other name for vitamin k
phyllo guinone
where do we get most of our vitamin k from
from e. coli in the colon
what is the other name for thrombocytes
platelets
what do thrombocytes do
turn into fibrin and clot
which population is at highest risk for vitamin k deficiency
newborns
why are newborns most susceptible to vitamin e deficiencies:
because e. coli has not populated their gut yet
what is vitamin c also known as
ascorbic acid
bleeding gums
tooth loss
poor wound healing
and small hemorrhages on the skin
characteristics of scurvy
acts as an antioxidant
synthesis of collagen
facilitates iron absorption in GI
functions of vitamin c
which protein is the most broken down in the body
collagen
scurvy
due to improper formation of collagen
anemia
due to poor iron absorption
main symptoms of deficiency of vitamin c
name for b1
thiamin
name for b2
riboflavin
name for b3
niacin
name of b5
pantothenic acid
name for b9
folate
name for b7
biotin
coenzymes or cofactors in energy metabolism
assist enzymes with energy release
without these coenzymes, enzymes cannot function
common functions of all b vitamins
what is the active form of b1 (thiamin) in energy metabolism
TPP
where is the vitamin b complex found in foods
animal flesh
in who does the b1 deficiency happen most
alcoholics and malnourished individuals
what is beriberi
a condition in which the heart becomes enlarged
if condition primarily affects the CV system:
wet beriberi
if condition primarily affects the nervous system
dry beriberi
is beriberi reversible
no!!
what is fad called (b2)
high energy carrier
does riboflavin deficiencies happen by themselves
no- usually with other water soluble vitamin deficiencies
what are the two forms of of niacin (b3)
nicotinamide and nicotinic acid
what is niacin used for in the body
used for synthesis of fatty acids (lipogenesis)
flushing of face and body
redness of faces, arms, and chest
tingling sensation
toxicity of b3 or niacin
what are the symptoms of pellagra (hint 4 d’s)
diarrhea, dermatitis, dementia, death
synthesis of non essential amino acids
glucose metabolism
function of b6
which three vitamin deficiencies can lead to anemia
E, C, B6
which source of b9 is the recommended form to eat? (folate or folic acid)
folic acid because it is easier to absorb in GI
AIDS IN DNA REPLICATION
affects red blood cell synthesis
central nervous system formation in fetal development
functions of folate or b9
what will happen to the baby if the mom is folate deficient
spina bifida, anencephaly
what is macrocytic anemia
large cell anemia
what is spina bifida
the failure for the spinal cord to close in utero
what is anencephaly
lack or incomplete development of brain and skull
what is the term for the combination of spina bifida and anencephaly
neural tube defects
what is the nickname for b12
cobalamine
essential in converting folate into active form
maintains the insulating lining that covers the nerve fibers, known as MYELIN SHEATH
functions of b12
why is b12 called cobalamine
because the structure contains cobalt
how is b12 synthesized (hint: same as K)
from bacteria
lower intrinsic factor
lower hydrochloric acid secretion
lower ability to release vitamin b12 from dietary protein
reasons why b12 absorption decreases as we age
macrocytic anemia
if lack of intrinsic factor, then pernicious anemia occurs (much worse)
diseases caused by lack of b12