Hydrolysis Reaction Mechanisms
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Last updated 12:29 PM on 3/25/26
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4 Terms
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What happens with Epoxide Hydrolase?
Epoxide / Arene oxide → add H2O → breaks forming a dihydrodiol
2
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What happens with Esterases/Amidases?
hydrolysis cleaves C–O (ester) or C–N (amide) → one side becomes a carboxylic acid, the other becomes alcohol/amine
3
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What happens with Peptidases / Proteases?
Break peptide bonds in proteins (–CONH–) → form individual amino acids or small peptides
4
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What do all hydrolysis reactions require?
Water (H₂O) → used to break bonds (ester, amide, peptide, phosphate, etc.)
