Module 1: Inorganic Pharmaceutical Chemistry - Part 3.1 - Group 5-8 Elements - 5A, 5B, 6A, 6B

Nitrogen group: N, P, As, Sb, Bi

a. Group 5A

b. Group 5B

c. Group 6A

d. Group 6B

a. Group 5A

Azote meaning without life.

a. N

b. P

c. As

d. Sb

e. Bi

a. N

Phlogisticated air

a. N2

b. H

c. O2

d. He

a. N2

Mephitic air

a. N2

b. H

c. O2

d. He

a. N2

Provides inert atmosphere for readily oxidizable pharmaceuticals.

a. N2

b. H

c. O2

d. He

a. N2

Refrigerant; for cryogenic preservation.

a. Liquid nitrogen

b. N2 gas

c. Nitrates

d. Nitrites

a. Liquid nitrogen

Liquid nitrogen temperature.

a. -176°C

b. -186°C

c. -196°C

d. -206°C

c. -196°C

St. Elmo's fire

a. N

b. P

c. As

d. Sb

e. Bi

b. P

Light carrier, stored underwater.

a. N

b. P

c. As

d. Sb

e. Bi

b. P

Essential constituent (in small amounts) of protoplasm, nervous tissues and bones.

a. N

b. P

c. As

d. Sb

e. Bi

b. P

Physiologic form of P which has the medicinal importance as antacid and cathartic.

a. Phosphorus

b. Phosphate

c. Phosphite

d. Phosgene

b. Phosphate

Waxy solid soluble in organic solvents.

a. White P

b. Red/Violet P

c. Black P

a. White P

Yellow or impure P.

a. White P

b. Red/Violet P

c. Black P

a. White P

Darkens in light and emits greening light, gives off white fumes with garlic odor with air.

a. White P

b. Red/Violet P

c. Black P

a. White P

Toxic and used as rat poison.

a. White P

b. Red/Violet P

c. Black P

a. White P

Intermediate property of b,ack and white P.

a. White P

b. Red/Violet P

c. Black P

b. Red/Violet P

Insoluble in organic solvent.

a. White P

b. Red/Violet P

c. Black P

b. Red/Violet P

Less chemical active compared to white P and nontoxic thus used in safety matches, pyrotechnics.

a. White P

b. Red/Violet P

c. Black P

b. Red/Violet P

Resembles graphite in texture.

a. White P

b. Red/Violet P

c. Black P

c. Black P

Produced from white P under high pressures.

a. White P

b. Red/Violet P

c. Black P

c. Black P

Air-stable; does not catch fire spontaneously

a. White P

b. Red/Violet P

c. Black P

c. Black P

The toxic P.

a. White P

b. Red/Violet P

c. Black P

a. White P

Lewisite metal which is the agent of choice for professional killers.

a. N

b. P

c. As

d. Sb

e. Bi

c. As

High affinity for -SH compound thus toxic to all types of cell.

a. As+3

b. As+5

a. As+3

Relatively less toxic.

a. As+3

b. As+5

b. As+5

General protoplasmic poison.

a. N

b. P

c. As

d. Sb

e. Bi

c. As

Salvarsan, Compound 606, Magic bullet.

a. Arsphenamine

b. Paris green

c. Scheele's green

d. Fowler's solution

e. Donovan's solution

a. Arsphenamine

First anti-syphilis discovered by Paul Ehrlich who is the father of chemotherapy.

a. Arsphenamine

b. Paris green

c. Scheele's green

d. Fowler's solution

e. Donovan's solution

a. Arsphenamine

Cupric acetoarsenite: Cu(C2H3O2)2 • 3Cu(AsO2)2

a. Arsphenamine

b. Paris green

c. Scheele's green

d. Fowler's solution

e. Donovan's solution

b. Paris green

Rodenticide, insecticide, pigment, blue colorant for fireworks.

a. Arsphenamine

b. Paris green

c. Scheele's green

d. Fowler's solution

e. Donovan's solution

b. Paris green

Cupric hydrogen arsenite.

a. Arsphenamine

b. Paris green

c. Scheele's green

d. Fowler's solution

e. Donovan's solution

c. Scheele's green

1% Potassium arsenite solution (KAsO2).

a. Arsphenamine

b. Paris green

c. Scheele's green

d. Fowler's solution

e. Donovan's solution

d. Fowler's solution

Former antileukemic.

a. Arsphenamine

b. Paris green

c. Scheele's green

d. Fowler's solution

e. Donovan's solution

d. Fowler's solution

Arsenic (III) iodide solution.

a. Arsphenamine

b. Paris green

c. Scheele's green

d. Fowler's solution

e. Donovan's solution

e. Donovan's solution

Formerly used for trypanosome infection, Malaria, TB, RA, diabetes.

a. Arsphenamine

b. Paris green

c. Scheele's green

d. Fowler's solution

e. Donovan's solution

e. Donovan's solution

Stibium.

a. N

b. P

c. As

d. Sb

e. Bi

d. Sb

Most important source of Sb.

a. Antimony glance

b. Antimony sulfide

c. Sb2S3

d. All

d. All - Antimony glance is aka Antimony sulfide (Sb2S3)

Color of antimony glance.

a. Red-brown

b. Red-orange

c. Yellow-green

d. Yellow-orange

b. Red-orange

Group 5A element used as anthelmintic, astringent, antiperspirant, emetic, and expectorant.

a. N

b. P

c. As

d. Sb

e. Bi

d. Sb

Beautiful meadow.

a. N

b. P

c. As

d. Sb

e. Bi

e. Bi

Used astringent, antiseptic, and internal protectant (antacid + inhibit Helicobacter pylori).

a. N

b. P

c. As

d. Sb

e. Bi

e. Bi

Helidac and Prevpac is preparation with?

a. N

b. P

c. As

d. Sb

e. Bi

e. Bi

Helidac®

a. Metronidazole + Tetracycline + Bismuth salicylate

b. Metronidazole + Trimethoprim + Bismuth salicylate

c. Lansoprazole + Amoxicillin + Clarithromycin

d. Lansoprazole + Amoxicillin + Clindamycin

a. Metronidazole + Tetracycline + Bismuth salicylate

Prevpac®

a. Metronidazole + Tetracycline + Bismuth salicylate

b. Metronidazole + Clarithromycin + Bismuth salicylate

c. Lansoprazole + Amoxicillin + Clarithromycin

d. Lansoprazole + Amoxicillin + Clindamycin

c. Lansoprazole + Amoxicillin + Clarithromycin

Metronidazole is DOC for the following except:

a. Pseudomembranous colitis

b. Trichomoniasis

c. Amoebiasis

d. Giardiasis

e. None

e. None

Tetracycline is DOC for the following except:

a. Chlamydia

b. Rickettsia

c. Mycoplasma

d. Giardiasis

e. None

d. Giardiasis - DOC for this is Metronidazole.

Bismuth ointment is how many percent?

a. 10%

b. 20%

c. 30%

d. 40%

c. 30%

Vanadium group: V, Nb, Ta

a. Group 5A

b. Group 5B

c. Group 6A

d. Group 6B

b. Group 5B

Group 5B except:

a. V

b. Nb

c. Ta

d. Cr

d. Cr - this is group 6B

Insulin mimetic effect but a drawback is metal toxicity.

a. V

b. Nb

c. Ta

a. V

Causes green tongue.

a. V

b. Nb

c. Ta

a. V

Unaffected by body fluids since its inert and its sheet-form is used for surgical repair of bones, nerve, tissues.

a. V

b. Nb

c. Ta

c. Ta

Oxygen group or Chalcogens.

a. Group 5A

b. Group 5B

c. Group 6A

d. Group 6B

c. Group 6A

Group 6A except:

a. O

b. Si

c. Se

d. Te

e. Po

f. None

b. Si - this is silicon (Group 4A), it should be Sulfur (S).

According to Priestly, O2 is:

a. Dephlogisticated air

b. Empyreal air

c. Acid former

d. Mephitic air

a. Dephlogisticated air

According to Scheele, O2 is:

a. Dephlogisticated air

b. Empyreal air

c. Acid former

d. Mephitic air

b. Empyreal air

According to Lavoisier, O2 is:

a. Dephlogisticated air

b. Empyreal air

c. Acid former

d. Mephitic air

c. Acid former

Oxides of Oxygen can be metallic (basic), nonmetallic (acidic), and amphoteric (e.g., Al2O3)

a. True

b. False

a. True

True about oxygen except:

a. 1/5 of air by weight (in free form)

b. 7/8 of water in minerals by weight (in combined states)

c. Chemically reactive (combines directly with elements except Hg, Ag, Au & Pt family members)

d. None

d. None

Ozone.

a. O

b. O2

c. O3

d. OH

c. O3

Powerful oxidizing agent used in bleach and as disinfectant.

a. O

b. O2

c. O3

d. OH

c. O3

Atmospheric or molecular Oxygen.

a. O

b. O2

c. O3

d. OH

b. O2

Nascent.

a. O

b. O2

c. O3

d. OH

a. O

Brimstone.

a. O

b. S

c. Se

d. Te

e. Po

b. S

Shulbari (enemy of Cu).

a. O

b. S

c. Se

d. Te

e. Po

b. S

Asupre.

a. O

b. S

c. Se

d. Te

e. Po

b. S

Constitutes 0.05% of Earth's crust.

a. O

b. S

c. Se

d. Te

e. Po

b. S

Sulfur may occur in free state and in combination such as:

a. Sulfides

b. Sulfites

c. Sulfates

d. All

d. All

Source of Sulfur.

a. Crude furnace

b. Calcarone

c. Stibium glance

d. a and b

e. All

d. a and b

Calcarone is a source of Sulfur synthesize by which process?

a. Haber's process

b. Lane process

c. Frasch process

d. Messerschmidt Process

c. Frasch process

Beta allotrope of Sulfur at equilibrium point which is 96°C.

a. Rhombic S

b. Monoclinic S

b. Monoclinic S

Alpha allotrope of Sulfur at room temperature and is stable.

a. Rhombic S

b. Monoclinic S

a. Rhombic S

Uses of sulfur except:

a. Scabicide and keratolytic ointment/ lotion

b. Antiseborrheic/Anti-dandruff (SeS2 )

c. Stimulates hair growth

d. Depilatory (as thioglycolate)

e. Stimulant cathartic

f. None

f. None

Depilatory form of Sulfur.

a. SeS2

b. Thioglycolate

c. HS2

d. H2SO4

b. Thioglycolate

Antiseborrheic/anti-dandruff.

a. SeS2

b. Thioglycolate

c. HS2

d. H2SO4

a. SeS2

Common form of S.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

a. Amorphous S

Formed of Sulfur obtained from heating S at 160-180°C.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

f. Liquid S

Rubber-like form of S which is obtained after cooling heated S.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

c. Plastic S

Milk of sulfur or lack sulfur.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

e. Precipitated S

Obtained by boiling S with lime and precipitating filtered solution with HCl.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

e. Precipitated S

Very fine pale-yellow powder, odorless, tasteless form of S which readily dissolves in CS2.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

e. Precipitated S

Form of Sulfur which is a component of Sulfur ointment.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

e. Precipitated S

Sulfur ointment is how many % Sulfur?

a. 5%

b. 10%

c. 15%

d. 30%

b. 10%

Component of Sulfur ointment:

a. Precipitated sulfur

b. Mineral oil

c. White ointment

d. a and b

e. All

e. All

Flowers of S.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

b. Sublimed S

Form of S which is fine yellow powder with faint odor and taste that slowly dissolve, usually incompletely soluble to CS2.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

b. Sublimed S

Form of Sulfur that is component of sulfurated lime.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

b. Sublimed S

Sublimed sulfur + lime (boiled).

a. Vleminck's Solution

b. Koppeschaar's Solution

c. Fehling's Solution

d. Lunosol Solution

a. Vleminck's Solution

Sulfurated lime.

a. Vleminck's Solution

b. Koppeschaar's Solution

c. Fehling's Solution

d. Lunosol Solution

a. Vleminck's Solution

Form of Sulfur obtained by treating sublimed S with NH3 to dissolve impurities, particularly As and to remove traces of acid.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

d. Washed S

Used to remove impurities in Sublimed S to form washed S.

a. Ammonia

b. Acetic acid

c. Nitric acid

d. 0.1 N Bromine

a. Ammonia

Has characteristics similar to sublimed S thus still has faint odor and taste.

a. Amorphous S

b. Sublimed S

c. Plastic S

d. Washed S

e. Precipitated S

f. Liquid S

d. Washed S

K2Sx • K2S2O3

a. Sulfurated potash

b. Potassa sulfurata

c. Lover of sulfur

d. Hepar sulfaris

e. All

e. All

Sulfurated potash is consists mainly of

a. K polysulfide

b. K thiosulfate

c. K sulfate

d. a and c

e. All

e. All

Sulfurated potash is irregular and is color liver brown but turns in what color with air?

a. Reddish orange

b. Greenish yellow

c. Yellow orange

d. Blue

b. Greenish yellow

Sulfurated potash possess H2S odor.

a. True

b. False

a. True

True about White lotion except:

a. Sulfurated potash + ZnSO4

b. Topical antifungal

c. Astringent, protective

d. Mild antimicrobial and antifungal

e. Used for treatment of skin parasitic diseases, psoriasis, scabies

f. None

f. None

White lotion component

a. Sulfurated potash

b. Precipitated S

c. ZnSO4

d. a and c

e. b and c

f. All

d. a and c

Antioxidant trace element which is used industrially as rubber. Form the word Selene meaning moon.

a. O

b. S

c. Se

d. Te

e. Po

c. Se

Keshan disease is deficiency in what?

a. O

b. Si

c. Se

d. Te

e. Po

c. Se