M121 Lec 5

The interaction between antibodies and antigens is __________.

not covalent

The FAB region of an antibody recognizes and binds to __________ on antigens.

epitopes

The FC region of an antibody binds to __________ proteins and FC receptors on immune cells.

complement

IgM is __________, low affinity but high valency.

pentameric

Antibodies enhance phagocytosis by __________ antigens.

marking

The main function of IgG is for __________ immunity.

adaptive

IgA is essential for __________ immunity.

mucosal

Degranulation is the release of enzyme-filled granules by __________ cells.

immune

Neutralizing antibodies prevent viral entry by blocking key __________ that viruses use to enter host cells.

receptors

IgE is typically bound to the surface of mast cells via the __________ receptor.

FCε

ADCC stands for __________-Dependent Cellular Cytotoxicity.

Antibody

The process of tagging pathogens for enhanced phagocytosis is called __________.

opsonization

The __________ pathway involves C1Q binding to the FC region of antibodies.

Classical

Antibody-dependent phagocytosis involves interactions between antibodies and __________ receptors on phagocytic cells.

FC

Antibodies can recognize __________ and discontinuous epitopes.

linear

Complement activation leads to the recruitment of __________ for immune responses.

phagocytes

Humoral immunity depends on the generation of __________ antibodies to prevent infection.

neutralizing

IgD acts as a marker for __________ cell maturation.

B

Macrophages can mediate __________ but are less dominant than NK cells in ADCC.

ADCC

Pathogens that bind IgA are swept away with __________ clearance.

mucus

Vaccine efficacy depends on generating __________ antibodies.

neutralizing

The __________ region of an antibody is responsible for effector functions.

FC