ap bio unit 4

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19 Terms

1
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What are the three steps of cell signaling?

Reception, Transduction, Response.

2
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What is short distance signaling?

Signaling that occurs when cells are touching, the fastest type of signaling, happens in spaces between cell membranes.

3
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What are ligands in long distance signaling?

Molecules that are released to travel short distances through diffusion or long distances in the bloodstream.

4
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What happens during the Reception step in cell signaling?

Ligand binds to receptor embedded in cell membrane, causing a shape change that transmits the signal into the cell.

5
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What is transduction in cell signaling?

The process of moving the signal from the cell membrane to the nucleus, often involving phosphorylation of proteins.

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What role do kinases play in cell signaling?

They transfer phosphates from ATP to other molecules during the transduction step.

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What are the two types of feedback in response to signals?

Negative Feedback and Positive Feedback.

8
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What is Negative Feedback?

A reaction that causes the cell to force changes to stop the effect of a signal, such as insulin in response to blood sugar.

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What is Positive Feedback?

A reaction that amplifies the effect of a signal until it is stopped, like contractions during birth.

10
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What occurs in the S phase of the cell cycle?

DNA Replication, where the cell goes from 2n to 4n.

11
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What is the role of cyclins and cyclin-dependent kinases (CdK’s) in the cell cycle?

They regulate the progression through the cell cycle.

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What are the 5 parts of Mitosis?

Prophase, Metaphase, Anaphase, Telophase, Cytokinesis.

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What happens during Prophase in Mitosis?

The nuclear membrane dissolves, nucleolus dissolves, and DNA condenses into chromosomes.

14
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What does cytokinesis achieve?

Cuts the cell in two, leading to the formation of two separate cells.

15
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What characterizes cancer in terms of the cell cycle?

Uncontrolled mitosis caused by random mutations affecting cyclins and CdK’s.

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How does cancer affect the duration of interphase?

It causes cells to spend less time in interphase.

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How do mutations in signaling proteins affect cell signaling?

They can alter or stop signal pathways, affecting cellular responses.

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What is a chromatid?

Condensed DNA structure, each chromatid is identical in mitosis.

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What is the purpose of the cell cycle?

To coordinate cell growth, DNA replication, and cell division.