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reproduction 1
how organisms make more individuals and pass on/change genotype 1
development
how to get a multicellular organism with differentiated cells, tissues, organs and a particular body plan
genotype
information stored in the DNA
phenotype
all structures, processes and behaviors of an organism
evolution
can only occur through changes in the hertiable traits of a biological population over generational time
phenotypic plasticity
the ability of individuals with a particular genotype to express different phenotypes as a result of environmental differences
monogenic traits
controlled by a single gene
polygenic traits
due to the action of multiple genes interacting with one another through intergrated pathways
continuous variation
variation clusters around average phenotype
discrete variable
a trait typically exhibits either one phenotype or another
phenotypic variation
always the result of the interaction between information from the environment and genotype
heritability
allows genotype component of phenotype to be passed on to offspring
overproduction of offspring
some of whom do not survive to reproduce
natural selection
differential survival of individuals with certain traits but not others
sexual selection
differential reproductive success of individuals with certain traits, but not others
DNA
double helix of base pairs containing the fundamental hereditary information of a living organism
chromatin
DNA combined with proteins
heterochromatin
condensed, densely packed
euchromatic
uncondensed, diffuse
chromosomes
discrete structures composed of chromatin
ploidy
number of types of chromosomes in a cell
haploid
1 N - one set of chromosomes
diploid
2N - two complete and different sets of chromosomes
polyploid
more than two versions of chromosomes
mitosis
eukaryote cell division that results in 2 genetically identical daughter cells
meiosis
eukaryote cell division that results in 4 genetically unique daughter cells
meiosis 1
eukaryote cell division that results in 2 genetically unique daughter cells
crossing over
the mechanism where homologous chromatids exchange corresponding segments of DNA
independent assortment
the mechanism where homologous pairs line up randomly in meiosis 1, leading to random chromosome combinations in daughter cells
meiosis 2
mitosis of 1 N daughter cells
purpose of genetic recombination
offspring genotypes are unique from parental genotypes
conjugation/lateral gene transfer
sexual reproduction of unicellular organisms
advantages of sexual reproduction
hedging bets and red queen hypothesis
hedging bets
if environmental conditions change, having offspring with a wide range of phenotypes will ensure that at least some will survive/pass on genes
red queen hypothesis
other organisms are constantly evolving, changing biotic conditions. genetic recombination creates favorbale combinations of genes to rapidly keep up
disadvantages of sexual reproduction
offspring only receive half a parents genes, difficult to mate, mates must be genetically compatible, offspring may be less fit than parents
gene
a segment of DNA that contains the instructions for building a specific protein or performing a particular function
locus
the physical location of a gene sequence on the DNA strand
allele
functionally different variants of a gene, diploid organisms will have two of these each gene
homozygous
a diploid individual that contains two functionally identical alleles of a particular gene
heterozygous
a diploid individual possessing two different alleles for a gene
simple dominance
organism will display the phenotype of the dominant allele if it inherits at least one
partial or incomplete dominance
each genotype is associated with a distinct phenotype
semi dominance
heterozygote’s phenotype is exactly intermediate between the phenotype of each homozygote
co-dominance
both alleles contribute equally to the pheontype; often they are also dominant over other alleles
epistasis
one gene alters the phenotypic effect of another gene
pedigree inheritance
the study of how traits are transmitted across generations by analyzing family trees to identify genetic patterns
autosomal dominant inheritance
only one copy of the altered allele (from either parent) is needed for an individual to show the trait or disorder, inidividuals who inherit the allele show the trait - theres no hidden carrier state
autosomal recessive inheritance
individuals must inherit two copies of the altered allele to show the trait or disorder
genetic linkage
genes are close together on the chromosome get inherited together
aneuploidy
atypical number of chromosomes (too many or too few)
gene dosage
number of copies of a particular gene
reproduction
the process that allows organisms to create new individuals
No alteration of Sexual Production
diploid organism has germ cells that undergo meiosis to product gametes for sexual reproduction
alternation of strategies
diploid organisms can undergo asexual reproduction or produce gametes via meiosis for sexual reproduction
alternation of generations
cells of diploid organisms undergo meiosis to product spores, which both grow and produce gametes via mitosis
unicellular asexual reproduction
binary fission
multicellular asexual reproduction
parthenogenesis, budding, regeneration, vegetative propagation
parthenogenesis
development of offspring from unfertilized gametes
budding
new individuals form as outgrowth from body of older individual
regeneration
growth of new individual from pieces of older individual
vegetative propagation
term for budding/regeneration in plants
spawning
release gametes into environment
intermittent organ
direct transfer of gametes
spermatophore
indirect transfer of gametes
gametes
haploid cells that fuse together in sexual reproduction
female
organisms that typically produce fewer, larger gametes
male
organisms that typically produce more, smaller gametes
pheromones
chemical substances used for communication between individuals of the same species
monoecious
a single individual produces both male and female gametophytes and may be capable of self-polination/cross polination
doecious
female and male gametophytes are produced by different individuals, who are incapable of self-pollination
development
formation of a complex multicellular organism from a single cell
polarity
establish axes of symmetry in early development
cleavage
growth via cell division throughout embryo development
migration
cells move in animal development
germ cells
give rise to gametes, are set-aside very early in development
somatic cells
all cells of the body, except those specialized for reproduction, all genetically identical
ectoderm
outermost germ layer, gives rise to skin and nervous system
mesoderm
middle germ layer, gives rise to muscles, circulatory systems, excretory systems, bones
endoderm
innermost germ layer, gives rise to lining of the gut and derivatives
gastrulation
radical movements reposition cells in the three germ layers to generate a mulit-layered organism
organogenesis
rearrangement of tissues to form distinct organs and organ systems
neurulation
formation of the neural tube (spinal cord and brain)
somitogenesis
formation of protective vertebrae and muscle blocks
differential gene expression
activation of different sub-sets of genes in different cells that is necessary for cell specialization
cellular signaling
signals sent between cells, receiving cells respond by activation or inhibition of different sub-sets of genes
cell fate and differentiation
differential gene expression and cell communication provide positional information to cells across the embryo, resulting in cell determination and differentiation
patterning
differential expression of homeotic genes establishes specialized body regions and location of structures
housekeeping genes
certain portions of the genome expressed by all cells, concerned with basic cell maintenance and function
transcription factors
regulate the expression of other genes, they may activate or inhibit expression of a given gene
induction
secretion of chemical signals by one group of cells to nearby target (responder) cells
morphogens
chemical signals
concentration and competency to respond
what determines how an inductive signal will be interpreted by a responder cell
cytoplasmic segregation
how embryos generate polarity; delocalization of maternally-derived mRNAs and proteins
determination
the process that sets a cell’s overall fate
differentiation
the process of becoming a specialized cell
stem cells
animals repair tissues using these cells that can migrate to a damaged area then differentiate into appropriate cell types
meristem cells
plants repair damage by having cells that can de-differentiate to become these cells and then re-differentiate to produce needed structures
homeotic genes
master control genes
purpose of homeotic genes
initiate a cascade of gene expression, affects the timing and amount of synthesis of proteins encoded by large number of genes (ex. Hox genes and Organ Identity genes)