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lymph
clear, transparent, sometimes faintly yellow fluid collected from tissues and flows in the lymphatic vessels
interstitial fluid
leaked fluid in the spaces between cells
endothelial cells
make up the walls of lymphatic capillaries to allow for fluids to easily enter the lymphatic capillaries, but make it hard to leave
lymphatic vessels
vessels that carry lymph
lymphatic trunks
lymphatic capillaries joined together to form collecting vessels
lymphatic valves
tissue flaps that act as one-way valves inside lymphatic vessels
lymphocytes
WBCs found in large amounts in lymphatic tissues
T lymphocytes (T cells)
mature in thymus
B lymphocytes (B cells)
mature in bone marrow
Natural killer (NK) cells
nonspecific defense cells that recognize and destroy virus-infected cells and cancer cells
macrophages
cells that phagocytize pathogens and old blood platelets
phagocytize
surround and destroy
pathogens
disease causing agents
mucosa-associated lymphatic tissue (MALT)
lymphatic tissue found in mucous membranes that line passageways open to the outside would (include respiratory, gastrointestinal, urinary, and reproductive tracts)
pharyngeal (adenoid) tonsils
lymphatic tissue at the back of the nasopharynx
palatine tonsils
lymphatic tissue found at the back of the mouth on the left and right side (most commonly infected)
lingual tonsils
lymphatic tissue found on either side of the base of the tongue
lymphatic nodules
small localized clusters of dense tissue formed by lymphocytes and macrophages
lymph nodes
small, bean-shaped structures found along the lymphatic vessels throughout the body that cleanse lymph and store and produce T and B cells
spleen
largest lymphatic organ in the body, located in the abdomen below the diaphragm; filters blood and activates an immune response if necessary
phagocytosis
phagocytes engulfing and destroying foreign matter and debris
neutrophils
phagocytize bacteria and cellular debris; most common leukocyte
macrophages
formerly monocytes; phagocytize pathogens in tissues
exocytosis
cells membranes fuse together to push debris from vesicles outside of cell
complement system
the circulation of more than 30 proteins in the blood plasma that work together to destroy foreign substances; complements/balances the specific and nonspecific defense systems
classical pathway
begins when one of the circulating complement proteins, usually inactive, recognizes antibodies bound to a target
complement proteins
proteins in the blood that work with the immune system cells and antibodies to defend the body against infection
alternative pathway
triggered when the C3b complement protein binds to foreign material
opsonins
proteins that make cells more attractive to phagocytes
mast cells
a type of cell found in connective tissue
membrane attack complex (MAC)
complement proteins that insert themselves into the bacterial cell membrane
interferons
proteins released by cells that have been infected with viruses
alpha interferons
produced by virus-infected leukocytes
beta interferons
produced by virus-infected fibroblasts
gamma interferons
produced by NK cells and T cells
prostaglandins
fatty acids involved in controlling inflammation, body temperature, and other chemicals
pyrogens
chemicals that raise the set-point temperature of the neurons in the hypothalamus