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what week do we see medial and lateral processes
wk. 5
what is the stomodeum lined with
ectoderm
what is the pharynx lined with
endoderm
neurocranium
-composed of cartilages and placodes which are supportive and related to the brain
-chondocranium + dermocranium
viscerocranium
-branchial arches and their derivatives (jaws and gills)
chondrocranium
-cartilage that protects and supports the brain
dermocranium
-true bone forms
-protective shell around the chondrocranium
how is the neurocranium different in mammals
-the dermocranium sits on top of the chondrocranium, this allows for expansion
what does the hindbrain develop into
-rhombomeres (series of 8 bulges)
what are somatomeres
-partially segmented paraxial mesoderm
what does mesenchyme develop into
-connective tissue and skeletal tissue
(loosely organized mesodermal, embryonic tissue)
what is ectomesenchyme derived from
neural crest cells
what does ectomesenchyme develop into
-dental and skeletal tissues of the oral cavity adn branchial arches
what does the midbrain and Rhb 1 & 2 provide material for
-bone and cartilage of the face
-1st branchial arch
what do NCC that arise from Rhbs 4,6, & 8 supply
-branchial arches 2-4
what is odontogenic epithelium
-tooth forming epithelium
-stimulates mesenchyme to develop dentin
what week does the buccopharyngeal membrane rupture
wk. 4
what are olfactory placodes, and when does formation begin
thick plates of cells that develop into the olfactory region of the nasal cavity
-wk. 4
nasal development is seen in what week
wk. 5
what week does the nasal pit form
wk. 5
nasal pit formation
-ectodermal cells of the nasal placode proliferate and push into the underlying NCC derived mesenchyme of the frontonasal proces
what epithelium forms the nasal pit
-invaginated sac of ectodermal epithelium
what does the medial nasal process and the frontonasal process give rise to
-mid portion of both the nose and upper lip (soft tissue)
-premaxilla and primary palate (hard tissue)
when does merging and fusion of facial processes occur
-wk. 6
what pushes the naso region toward the midline and when does this occur
-maxillary process
-end of wk. 6
what does the growth of the maxillary process form
-naso-optic groove
-bucconasal groove
what forms the upper lip
-2 maxillary processes
-2 medial nasal processes
what forms the lower lip
fusion of the mandibular process
what region carries the upper incisors
premaxilla
what forms the ethmoid bone
-trabecular cartilages
what does the basal plate form
-sphenoid and occipital bones
when does the formation of the nasal fin occur
wk. 6
what forms the nasal fin
-fusion of the medial nasal process with the maxillary process
what forms the oronasal membrane
-thinning of the nasal fin
what does the complete breakdown of the nasal fin form
-primitive choana
what week does the primary choanae form
wk. 6
what forms the nasolacrimal duct
naso-optic groove
frontonasal process forms what
medial and lateral nasal processes
what forms an intermaxillary segment which ends up forming what
-medial nasal process
-upper lip (philtrum)
-upper jaw
-primary palate -> premaxilla
the maxillary process forms what
-upper lip
-upper jaw -> maxilla
-secondary palate
when does the formation of the secondary palate begin
-wk. 7-8
-ends at 3 months
what 3 major outgrowths appear during the development of the secondary palate
-nasal septum
-frontonasal process
-palatine shelves
what defines the primitive mouth
-1st branchial/pharyngeal arch
which cleft type is the most common
-cleft lip and palate
(bilateral clefting is least common)
what results in orofacial clefting
-lack of maxillary and palatal fusions