Lecture 11 endocrine disruptors
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4 Terms
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Endocrine disruptors mechnism
The chemicals mimics our own hormones
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Diethylstilbestrol
DES, mend to prevent miscarage, mom has increased breast cancer risk, kids and grandkids have higher risk of cancer, premature birth, cerebral palsy, ADHD
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What makes EDCs so special
• Endocrine disruption can be result of various
modes of action, in various organs
• Age at exposure and latency from exposure
• Transgenerational, epigenetic effects
Traditional risk assessment may be outdated...
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How to deal with uncertainties
More research, implement safety margins, realistic expectations
Note 
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