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Ways of regulating enzymes
allosteric effector
competitive inhibition
noncompetitive inhibition
cooperativity
Competitive inhibition
substance the enzyme by occupying the active site
Noncompetitive inhibition
substance inhibits the enzyme by binding to a location other than the active site and changes the shape of the enzyme
Ribosomes are manufactures in the…
nucleus
Rough ER contains
ribosomes
Function of rough ER
assembly of proteins
Function of smooth ER
synthesis lipids and hormones
Function of lysosomes
contain digestive enzymes to break down food and bacteria
Function of peroxisomes
break down various substances
Tight Junctions
prevents the passage of materials between cells.
characteristic in cells lining the digestive tract
Gap Junctions
narrow tunnels between animal cells that allows the passage of ions and small molecules
Plasmodesmata
narrow channels between plant cells
Characteristics of Prokaryotes
No nucleus
single DNA
smaller ribosomes
peptidoglycan cell walls
Forms of Passive Transport
Diffusion
Osmosis
Facilitated Diffusion
Reactants of Cellular Respiration
Glucose and Oxygen
Products of Cellular Respiration
Carbon Dioxide, Water, and energy
Where does glycolysis occur
cytoplasm
Net ATP produced in glycolysis
2
Pyruvate produced in glycolysis ( 3 Carbon molecule)
2
What does the Krebs Cycle produce
2 FADH, 6 NADH, 2 ATP, 2 CO2
What is the final electron acceptor in the electron transport chain
oxygen
Number of ATP produced in ETC
32
Where does the Kreb Cycle occur
intermembrane space of mitochondria
Where does ETC occur
intermembrane space of mitochondria
Reactants of Photosynthesis
CO2, H2O, and light
Products of Photosynthesis
Glucose and O2
Calvin Cycle
converts CO2 to glucose
Where does the Calvin Cycle occur
stroma
Where does the light reactions occur
Thylokoids
Another name for the Calvin Cycle
light independent reactions
Chromosomes
tightly coiled bodies of chromatin
G1 Phase
Growth
S Phase
Growth and duplication of DNA
Synthesis
G2 Phase
growth and preparation for cell divison
Prophase
Nucleoli disappears
chromatin condenses
nuclear envelope breaks down
mitotic spindle assembles
Metaphase
Chromosomes are distributed across metaphase plate
Anaphase
Chromosomes are separated into chromatids
microtubules pull chromosomes to opposite poles
Telophase
Nuclear envelope develops around each pole
nuclei appears
Prophase I
prophase of mitosis
synapsis
tetrads
crossing over
Synapsis
homologous chromosomes pair
Metaphase I
Homologous chromosomes spread across metaphase plate
Anaphase I
Homologous chromosomes pulled to opposite poles
Prophase II- Telophase II
just like mitosis
Types of Genetic Variation
Crossing over
Independent Assortment
Random joining of gametes
G1 Checkpoint
if conditions are not appropriate or if the cell is genetically programmed not to divide it remains in extended phase
G2 Checkpoint
evaluates the accuracy of DNA replication and signals whether or not to begin mitosis
M Checkpoint
occurs during metaphase
ensures that microtubules are attached to kinetochores
Factors that influence onset cell divison
Checkpoints
Cyclin dependent kinases
growth factors
density dependent inhibition
anchorage dependence
Cyclin Dependent kinases
activate proteins that regulate the cell cycle
Growth Factors
plasma membrane receptors sense external molecules that stimulate the cell to divide
Density dependent inhibition
cells stop dividing when surrounding cell density reaches max
Anchorage dependence
cells only divide when attached to external surface like neighboring cell
Epistasis
one gene affects the phenotypic expression of another gene
Pleiotropy
a single gene has more than one phenotypic expression
Helicase
unwinds DNA helix
Topoisomerases
break and rejoin the double helix
removes twists and knots
Primase
initiates DNA replication
RNA primers
short segments of RNA nucleotides used to initiates DNA replication
DNA polymerase
attaches to RNA primers and begins adding DNA nucleotides to the complement strand
Leading strand
assembled continuously
Lagging strand
assembled in short Okazaki fragment
DNA ligase
joins Okazaki fragments
processes in protein synthesis
transcription
RNA processing
translation
steps of transcription
initiation
elongation
termination
Initiation of Transcription
RNA polymerase attaches to promoter region on DNA
unzips DNA in two strands
contains TATA
Elongation
RNA nucleotides are assembled on DNA template
occurs in 5-3 direction
Termination
RNA polymerase reaches a sequence that serves a termination point