2 - Wound Healing 2024 (Rush Surgery)

80%

The tensile strength of a wound only reaches only about _____% of uninjured issue

Zinc

Zinc is a necessary cofactor of RNA and DNA polymerase, and deficiencies have been linked to poor early wound healing.

Deficiency in _______ (vitamin) results in delayed early wound healing

Fibroblast growth factor (FGF)

FGF is mitogenic for endothelial cells, fibroblasts, keratinocytes, and myo- blasts; stimulates wound contraction and epithelialization; and induces the production of collagen, fibronectin, and proteoglycans. It is an important mediator of angiogenesis

___________ (growth factor) stimulates wound contraction

Stage __ pressure ulcers arerepresented by the presence of non- blanching erythema of intact skin

Stage I

Stage ___ pressure ulcers are characterized by partial-thickness skin loss involving the epidermis or dermis

Stage II

Clinically, the ulcer is manifested as a blister, abrasion, or shallow crater

Stage ___ pressure ulcers are full-thickness skin loss with involvement of the underlying subcutaneous tissue and may extend down to but not through underlying fascia

Stage III

Stage _____ pressure ulcers represent full-thickness skin loss with extensive destruction or tissue necrosis of underlying structures, which may include muscle and bone.

Stage IV

Vitamin D

Vitamin D is required for normal calcium metabolism, but it is also involved in promoting immune function in the skin

Vitamin ____ serves an immunomodulatory role in wound healing.

Proliferative phase

During this phase granulation tissue is formed through angiogenesis, fibroplasia, and epithelialization

It is during the ______ phase of wound healing that the scaffolding for tissue repairis laid.