Intro to Neuropharm Cocaine and Amphetamines

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Last updated 8:31 PM on 4/28/25
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9 Terms

1
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Blocks reuptake of DA, NE, and 5-HT

What is cocaine’s mechanism of action?

2
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Amphetamines and Methamphetamines

Synthetic drug structurally related to DA

3
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amphetamine

indirect catecholamine agonist

4
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amphetamine

Stimulate DA and NE release and block reuptake

5
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Enters nerve terminal by DAT and stimulates release of DA from vesicles; and alters DAT to act in the reverse direction to release DA into the synapse

What are the two ways amphetamines stimulates massive DA release?

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Amphetamines

Cause heightened alertness, increased confidence, feelings of exhilaration, reduced fatigue, and generalized sense of well-being. Reduced sleep-time, especially REM sleep, can enhance athletic performance

7
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Amphetamine

What is the base of Adderall?

8
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Adderall

What is a drug treatment for ADHD?

9
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Schizophrenia

Repeated methamphetamine use can lead to a psychotic state that is similar to?

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