Analytical Chemistry Overview

These flashcards cover fundamental concepts, definitions, and methods in Analytical Chemistry as discussed in the notes.

Analytical chemistry focuses on __ of matter.

determining the composition and structure

Qualitative analysis reveals the __ of the constituents in a sample.

identity

Quantitative analysis indicates the __ of each substance in a sample.

amount

Classical wet procedures do not use any instruments except for an __.

analytical balance

methods are used to determine the mass of the analyte.

Gravimetric

Volumetric or Titrimetric methods measure the __ of a solution.

volume

Electroanalytical methods measure __ properties like voltage and current.

electrical

Spectroscopic or Optical methods explore the interaction between __ and analyte atoms or molecules.

electromagnetic radiation

The first step in quantitative analysis is __ a method.

picking

Sampling is the process of collecting a small mass of a material that represents the __ of the material.

bulk

The third step of processing a sample can involve preparing a __ sample.

laboratory

Substances that may interfere with the measurement step are called __.

interferences

Calibration is the process of determining the __ constant k.

proportionality

Calculating results involves computing analyte concentrations from __ data.

experimental

An analyte is a __ to be studied by quantitative measurements.

constituent

An assay is a highly accurate __ determination of a constituent.

quantitative

Background in a measurement arises from sources other than the __ itself.

analyte

A __ is a simulated matrix used to analyze a sample without the actual sample.

blank

Concentration refers to the amount of a substance present in a given mass or __ of another substance.

volume

A major constituent is defined as being greater than __ percent.

10

The smallest amount of an analyte that can be detected is called the __ limit.

detection

An internal standard is a compound added to all calibration standards in a __ known amount.

constant

Masking is the treatment of a sample with a reagent to prevent __ with the analyte.

interference

A primary standard is a substance whose purity and stability are particularly well __.

established

Procedure refers to a description of the practical steps involved in an __.

analysis

Sensitivity is the change in the response from an analyte relative to a small __ in the amount being determined.

variation

Standard addition is a method whereby the response from an analyte is measured before and after adding a __ amount of that analyte to the sample.

known

Standardization determines the concentration of an analyte from its reaction with a __ standard.

primary

The technique is based on the principle upon which a group of __ is based.

methods

Validation of methods involves analyzing standards with an accepted __ content.

analyte