DNA Repair and Recombination
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Last updated 7:17 PM on 8/28/25
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5 Terms
1
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What are common sources of DNA damage?
Replication errors, chemical mutagens, and radiation.
2
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What are the three major DNA repair systems?
Base excision repair (BER), nonhomologous end joining (NHEJ), and homologous recombination (HR).
3
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Which repair system is error-prone and why?
NHEJ, because it joins DNA ends without a template.
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Which repair system is mostly error-free?
Homologous recombination, because it uses a template strand.
5
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What is the link between DNA repair defects and cancer?
Impaired repair allows mutations to accumulate, promoting cancer development.
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