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Compliance
ability to act accordingly to an order or request; following recommendations
Adherence
The extent to which a persons behavior such as taking medication, following a diet, and/or executing lifestyle changes, corresponds with agreed upon recommendations from a health care provider
Persistence
the act of continuing the treatment as prescribed
Issues with managing medications
30% of prescriptions may not ever be picked up (primary non adherence)
adherence among patients with chronic conditions avg only 50%
8 out of 10 adults take at least one medication
System Impact
cost increase
employer cost increase
(loss of employer productivity)
unreached potential of healthcare advances; population health goals
increase in nursing home and hospital admissions
Patient Impact
morbidity (disease worsening)
mortality (increased death)
quality of life affected
reduced treatment effectiveness
withdrawal systems
psychosocial complications
Types of Non-Adherence
primary- Rx never filled/picked up
secondary- Rx started but doesn’t continue
intentional- pt chooses not to take medicine
unintentional- omissions, delayed doses, additional doses, incorrect administration
“White Coat Adherence”
Predictors of Non Adherence
psychological conditions
presence of cognitive impairment
asymptomatic disease states
inadequate follow up or discharge planning
medications with high side effect profile
poor provider relationships
barriers to taking the meds
Unintentional, Preventable NA
forgetting doses
omitting doses
not having meds when away from home
misunderstanding regimen demands
running out of meds
improper admin techniques
cost issues
feeling like med is unecessar
adherence measured
proportion of days covered PDC
PDC= (# of days in a period “covered”/ # of days in period) x 100%
PDC OF 0.8 IS GOOD
PDC OF 0.9 FOR HIV IS GOOD