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Clinical Chemistry Flashcards
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Which disease state is least affected by fasting?
Elevated HDL
What happens more often during kidney disease?
Metabolic acidosis
Insecticide poisoning affects what enzyme?
Cholinesterase
Most abundant beta globulin in CSF?
Transferrin or beta-2 transferrin
An analyte greatly affected by hemolysis:
Potassium
Marker for hepatocellular damage:
ALT
What routine test is added for assessing lipids associated with atherogenic effects?
Apolipoprotein
All of the following runs should be rejected except:
1 2S
Preventive maintenance:
Fixing things before they break
Least effective test for pheochromocytoma:
HMA
A step in the glycolytic pathway that is irreversible:
Fructose-6-phosphate → Fructose-1,6 Biphosphate
What does the numerator on the Henderson-Hasselbach equation denote?
Lungs
Enzymes that are used in analytical tests should be in ____ temperature.
Optimum
Which of the following is a secretory function of the liver?
Production of bile
In turbidimetry, what type of light is measured?
Transmitted
Forms of calcium in the human body, except:
Enzyme-bound
TAG (1036 mg/dL) correlates more to:
CHD
All of the following are affected in increased levels of ALT except:
Thyroid
NOT elevated in liver function test:
Bone disease
Type 1 APR except:
Complement
End product of protein metabolism:
Urea
Analytical technique involving the use of ISE:
Potentiometry
Convert 11 x 10^-3 to decimal notation:
0.011
Convert 12.51 to nearest tenths:
12.5
What is the primary cause of dyslipidemia?
Genetic mutations
Second most abundant protein in CSF?
Transferrin
Most abundant apolipoprotein in HDL?
Apo-A1
When does blood sugar levels usually rise?
During and after meals
What increased result can be seen from a student who’s been studying for an examination and hasn’t been eaten all day?
Glucagon
Method most commonly used in creatinine determination:
Jaffe
In serum protein electrophoresis, what can differentiate monoclonal from polyclonal gammopathy?
Gamma globulin spike
Analytical tool used as a measure of uncertainty:
Coefficient of Variation
Unique protein that is redissolved at 100 deg C but precipitates at 45-50 deg C is indicative of what disease?
Multiple myeloma
With the exception of occupational settings, which of the following is the strongest indicator for mercury consumption?
Fish Consumption
Which is not widely frequently used for determining thyroid function:
LC-MS
Which of the following precedes GC/MS?
Immunoassay
Increased pCO2 indicates what condition?
Respiratory acidosis
A patient’s ABG shows the following: pH: High pCO2: Normal HCO3: High What is the most likely interpretation?
Metabolic alkalosis
What is the concern when a patient is isolated in a room with negative air pressure?
Airborne
All are secretory serum enzymes, except:
Transaminase
What blood gas parameters measure the alveolar ventilation?
PCO2
In the liver, bilirubin is converted to:
Bilirubin diglucuronide
Convert 0.5 dL to L:
0.05
Convert 0.50 um to nm:
500
What is the reference method of glucose determination?
Hexokinase
What is the coupling enzyme utilized in hexokinase method:
G6PD
What method is specific only for B-D glucose:
Glucose oxidase
To convert pCO2 to carbonic acid, the former should be multiplied by:
0.03
Which of the parameter indicates respiratory acidosis?
Increased PCO2
What is the anticoagulant of choice for lipoprotein measurement:
Heparin
How to convert BUN to urea:
X 2.14
What is the analyte that maintains osmotic pressure?
Sodium
What blood gas parameter measures alveolar ventilation:
PCO2
Which of the following is a marker of preterm delivery:
Fibronectin
The measurement of BUN using spectro with an amount of 1016 mg/dL is equivalent to which of the following:
Nitrogen
Indicator of relative concentration:
Dilution factor
What is the ISE membrane specific to potassium?
Valinomycin
What analyte maintains colloidal pressure?
Albumin
Recommended initial thyroid function test:
Thyroid-stimulating hormone (TSH)
Chylomicrons are present in which of the following dyslipidemias?
Deficiency in lipoprotein lipase activity
Transportation of 60-75% of the plasma cholesterol is performed by:
Low-density lipoproteins
The most important buffer pair is the:
Bicarbonate/carbonic acid pair
90% of the copper present in the blood is bound to:
Ceruloplasmin
A critically ill patient becomes comatose. The physician believes the coma is due to hepatic failure. The assay most helpful in this diagnosis is:
Ammonia
The protein that has the highest dye-binding capacity is:
Albumin
Which of the following represents the end product of purine metabolism in humans?
Uric acid
All of the following alters glucose levels, except:
Vegetable diet
What is not an acute phase protein?
Vitamin B12
Marker for thyroid autoantibody:
Tg Ab
Type 1 hypersensitivity protects from:
Parasite
Unit of C3:
mg/dl
Parameters used to measure uncertainty:
SD
What anticoagulant is used for lipoprotein?
EDTA
Primary protein responsible for maintaining oncotic pressure:
Albumin
Which is correct regarding the chemistry techniques and their corresponding measurement of light?
Turbidimetry: transmitted
If you're not exposed working with mercury, how can you acquire it?
Fish intake
Where is calcitonin produced?
Parafollicular
What is tested when a patient had pesticide poisoning?
Cholinesterase
What is preventive maintenance?
Help Identify potential issues before they cause breakdowns
All of the following can be seen on a blood smear except:
S. stercoralis
First stain used in AFB:
Carbol fuchsin
Test to differentiate Neisseria from Acinetobacter:
Oxidase
Campylobacter grows optimally at what temperature?
42 deg C
Specimen of choice for VZV:
Vesicular lesion
Test used to differentiate E. coli from Shigella:
Acetate
Protozoan that has 8 nuclei:
E. coli
Which hepatitis virus is transmitted via fecal-oral route?
HAV
Not included in counting of Plasmodium spp.
Sporozoites
Specimen of choice for rickettsiae:
Blood
Most significant in soft tissue abscess:
Staphylococcus pyogenes
TSI A/A with swarming:
Proteus
Large lateral spine belongs to which Schistosome?
S. haematobium
Most ideal to be used for mass fecal examination?
Kato Katz
How many percent of formalin is used in preserving protozoan cyst?
10
A patient suspected with an otitis media infection should be tested with:
Optochin disk
Actinomycetes are:
Gram positive bacilli, facultative
Symptoms of food poisoning due to S. aureus occurs within:
2-6 hrs
Which is not included in water quality testing?
Salinity
Gram positive bacilli with rectangular ends and bamboo pole appearance:
Bacillus
Which of the following is under BSL 2?
S. aureus